ENVIRONMENTAL HEALTH APPLICATIONS OF MASS SPECTROMETRY

质谱法在环境健康方面的应用

• 批准号: 3918689
• 负责人: K B TOMER
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3918689
• 关键词: bioassay; chemical structure; chromatography; corticosterone; diethylstilbestrol; dioxins; drug metabolism; environmental health; epidermal growth factor; health science research; hormone metabolism; mass spectrometry; phospholipids; phthalates; toxin metabolism

One of the components of the mass spectrometry workgroup mission is to provide other groups within LMB and NIEHS access to mass spectrometric analyses on a service basis. The workgroup provides the following services on an ongoing basis: 1) low and high resolution electron impact (EI) mass spectra; 2) low and high resolution chemical ionization (CI) mass spectra; 3) negative ion chemical ionization (NICI) mass spectra: 4) gas chromatography/mass spectrometry (GC/MS) in conjunction with EI, CI and NICI MS; 5) thermospray (TSP) liquid chromatography/mass spectrometry (LC/MS) in conjunction with CI and NICI MS; 6) fast atom bombardment (FAB) under both positive and negative ion conditions; 7) continuous flow FAB/MS and FAB/MS/MS under both positive and negative ion conditions; and 8) tandem MS in combination with positive and negative ion FAB, EI and CI MS. During the past year approximately 691 analyses have been performed on a service basis (not including collaborative work).

质谱学工作组任务的组成部分之一 为LMB和NIEHS内的其他团体提供访问MASS的机会 在服务基础上进行光谱分析。工作组提供 持续提供以下服务：1)低价和高价 分辨电子轰击(EI)质谱图；2)低和高 分辨化学电离(CI)质谱图；3)负离子 化学电离(NICI)质谱图：4)气相色谱/质谱图 光谱(GC/MS)与EI、CI和NICI MS联用； 热喷雾(TSP)液/质联用(LC/MS) 结合CI和NICI MS；6)快原子轰击(FAB) 在正负离子条件下；7)连续流动 正负离子下的FAB/MS和FAB/MS/MS 条件；8)串联质谱仪结合正极和正极 负离子FAB、EI和CI-MS 在过去的一年里，大约进行了691次分析 以服务为基础(不包括协作工作)。