Markers of Autism and Gender Incongruence in Children (MAGIC): Cognition in Autistic and Non-autistic Gender-incongruent Children and Their Families
儿童自闭症和性别不一致的标志(MAGIC):自闭症和非自闭症性别不一致儿童及其家庭的认知
基本信息
- 批准号:ES/W000946/1
- 负责人:
- 金额:$ 68.5万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2022
- 资助国家:英国
- 起止时间:2022 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
This project is a collaboration between the University of Kent and the Tavistock and Portman NHS Foundation Trust, which hosts Europe's largest gender identity development service (GIDS). Our aim is to understand gender incongruence (when birth-assigned sex does not align with experienced gender) and its striking link with autism spectrum disorder (ASD), which is diagnosed in gender-incongruent children at almost 10 times the population rate. The nature and underpinnings of this co-occurrence have not yet been researched systematically. Hence, clinicians, educators, and parents are trying to support a marginalised and vulnerable population of children with insufficient understanding of gender incongruence, or why it co-occurs with ASD at such a striking rate.The importance of investigating this co-occurrence was highlighted by a recent judicial review (Bell v Tavistock, Dec 2020) and there is consensus that services need to be tailored and adapted for gender-incongruent autistic children and their families. Therefore, this project is timely, and will address a major gap in current research. The investigators are leading child psychologists and psychiatrists, with substantial experience of working with the proposed populations and researching gender identity. Over three years, the team proposes to examine how gender incongruence may overlap with ASD in a series of studies, involving 200, 7- to 14-year-old, children/young people and their families who fall into one of the following four groups:1) cisgender neurotypical children (i.e. children whose gender identity corresponds to their birth-assigned sex and who do not have ASD)2) cisgender children with ASD3) gender-incongruent neurotypical children4) gender-incongruent children with ASDThe series of studies will be conducted remotely by the research team and will use a wide range of implicit and explicit measures of various aspects of gender identity, as well as potential cognitive markers of these aspects, to understand whether:- ASD is associated with different cognitions in cisgender and gender-incongruent children- Gender incongruence is associated with different cognitions in autistic and non-autistic children- Gender identity develops differently in neurodivergent and neurotypical children across the dimensions of gender flexibility, gender typicality, gender expression, and gender dysphoria- Theory of mind, cognitive flexibility, and/or alexithymia relate to the development of atypical forms of gender identity- Expressions and strength of gender, as well as cognitive markers of gender incongruence, run in the families of autistic and non-autistic, cisgender and gender-incongruent childrenAnswering these questions will identify possible 'cognitive markers' of gender incongruence that have the potential to revolutionise our understanding and support of gender-incongruent children, and inform theories of gender development and ASD. Cognitive markers represent intermediate levels between genes and behaviour that can be tapped using psychological measures, and which overcome problems associated with identifying children only on the basis of (often highly diverse) behavioural presentations and self-reports. This research will undoubtedly allow for enhanced assessments of children referred to GIDS and aid the development of more personalised support. We will engage stakeholders throughout, including parents and young people, specialist NHS Gender Services for children, CAMHS, schools, and support services for autistic people (e.g., National Autistic Society, Autistica). We will also produce a website, will publish our findings open access, and will provide a free workshop for parents, teachers, and clinicians. The uniqueness of this study means that it will generate findings of international significance likely to have an impact on theory building, clinical and educational practice, and societal understanding in the UK and beyond.
该项目是肯特大学与塔维斯托克和波特曼NHS基金会信托基金会之间的合作,该基金会托管欧洲最大的性别认同发展服务(GIDS)。我们的目标是了解性别不一致(当出生分配的性别与经验性别不一致时)及其与自闭症谱系障碍(ASD)的惊人联系,ASD在性别不一致的儿童中被诊断出的比例几乎是人口的10倍。这种同时发生的性质和基础尚未得到系统的研究。因此,临床医生、教育工作者和家长都在努力帮助边缘化和弱势群体的儿童,他们对性别不一致或为什么它与ASD以如此惊人的速度同时发生缺乏了解。(贝尔诉塔维斯托克,2020年12月),人们一致认为,需要为性别不一致的自闭症儿童及其家庭量身定制和调整服务。因此,这个项目是及时的,将解决目前研究中的一个主要空白。研究人员是领先的儿童心理学家和精神病学家,具有与拟议人群合作和研究性别认同的丰富经验。在三年的时间里,该团队建议在一系列研究中研究性别不一致如何与ASD重叠,涉及200名7至14岁的儿童/青少年及其家庭,他们属于以下四组之一:1)顺性神经型儿童(即,性别认同与出生性别一致且未患ASD的儿童)2)患有ASD的顺性别儿童3)性别不一致的神经型儿童4)性别-研究小组将远程进行一系列研究,并将使用广泛的内隐和外显测量性别认同的各个方面,以及这些方面的潜在认知标记,以了解是否:- ASD与顺性别儿童和性别不一致儿童的不同认知相关-性别不一致与自闭症儿童和非自闭症儿童的不同认知相关-神经发散儿童和神经典型儿童的性别认同在性别灵活性,性别典型性,性别表达和性别焦虑的维度上发展不同-心理理论,认知灵活性,和/或述情障碍与性别认同的非典型形式的发展有关-性别的表达和强度,以及性别不一致的认知标记,在自闭症和非自闭症的家庭中运行,cisgender和性别不一致的儿童回答这些问题将确定性别不一致的可能“认知标记”,这些标记有可能彻底改变我们对性别的理解和支持。不协调儿童,并告知性别发展和ASD的理论。认知标记代表了基因和行为之间的中间水平,可以使用心理测量方法加以利用,克服了仅根据(往往是高度多样化的)行为表现和自我报告来识别儿童的问题。这项研究无疑将有助于加强对转介到GIDS的儿童的评估,并有助于发展更个性化的支持。我们将让利益相关者参与进来,包括父母和年轻人,为儿童提供的专业NHS性别服务,CAMHS,学校和自闭症患者的支持服务(例如,全国自闭症协会,自闭症)。我们还将制作一个网站,将公布我们的研究结果开放获取,并将为家长,教师和临床医生提供免费研讨会。这项研究的独特性意味着它将产生具有国际意义的发现,可能对英国及其他地区的理论建设,临床和教育实践以及社会理解产生影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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David Williams其他文献
カルタヘナ法と関わる組換え生物生ワクチン
卡塔赫纳法相关重组生物活疫苗
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:0
- 作者:
Hokyung Oh;Jinho Shin;Manabu Ato;Xiao Ma;David Williams;Kiwon Han;Yang Jin Kim;Hyung Goo Kang;Kikyung Jung;Kentaro Hanada;Masaki Ochiai;Pham Van Hug;Sangmi Park;and Chiyoung Ahn;花田賢太郎 - 通讯作者:
花田賢太郎
Affinity purification of secreted alkaline phosphatase produced by baculovirus expression vector system
杆状病毒表达载体系统产生的分泌型碱性磷酸酶的亲和纯化
- DOI:
10.1385/abab:90:2:125 - 发表时间:
2001 - 期刊:
- 影响因子:3
- 作者:
Fuming Zhang;M. Wolff;David Williams;Katie Busch;Sybil C. Lang;D. Murhammer;R. Linhardt - 通讯作者:
R. Linhardt
Technical Section: O-Buffer based IFT watershed from markers for large medical datasets
技术部分:基于 O-Buffer 的大型医学数据集标记的 IFT 分水岭
- DOI:
10.1016/j.cag.2007.08.008 - 发表时间:
2007 - 期刊:
- 影响因子:0
- 作者:
E. Coto;Sören Grimm;David Williams - 通讯作者:
David Williams
Severe falciparum malaria: a case report.
严重恶性疟疾:病例报告。
- DOI:
- 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
Tasaduq Fazili;M. Fogle;R. Eagle;M. Camp;David Williams;Aaron Boyd - 通讯作者:
Aaron Boyd
Cost-effective designs of field service for electronic systems
电子系统现场服务的经济高效设计
- DOI:
10.1109/test.2005.1584005 - 发表时间:
2005 - 期刊:
- 影响因子:0
- 作者:
Yu;David Williams;T. Ambler - 通讯作者:
T. Ambler
David Williams的其他文献
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{{ truncateString('David Williams', 18)}}的其他基金
WoU-MMA: Astrophysics with Very High-Energy Gamma Rays
WoU-MMA:极高能伽马射线的天体物理学
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- 资助金额:
$ 68.5万 - 项目类别:
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WoU-MMA: Development of the Optical Alignment Systems for the Medium-Sized Telescopes of the Cherenkov Telescope Array
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2320587 - 财政年份:2023
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$ 68.5万 - 项目类别:
Standard Grant
Nanoscale interactions of candida species with oral bacteria and surfaces
念珠菌物种与口腔细菌和表面的纳米级相互作用
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NE/V019856/1 - 财政年份:2021
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$ 68.5万 - 项目类别:
Research Grant
Cyclization Strategies and Methodologies Toward the Synthesis of Complex Natural Products
复杂天然产物合成的环化策略和方法
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2102587 - 财政年份:2021
- 资助金额:
$ 68.5万 - 项目类别:
Standard Grant
WoU-MMA: Astrophysics with Very-High-Energy Gamma Rays
WoU-MMA:极高能伽马射线的天体物理学
- 批准号:
2011420 - 财政年份:2020
- 资助金额:
$ 68.5万 - 项目类别:
Continuing Grant
Advances of Methodology and Design for the Synthesis of Complex Polycyclic Natural Products
复杂多环天然产物的合成方法与设计进展
- 批准号:
1665356 - 财政年份:2017
- 资助金额:
$ 68.5万 - 项目类别:
Continuing Grant
Paternal obesity-associated DNA methylation: an investigation into its reproducibility, reversibility and association with fetal growth restriction
父亲肥胖相关的 DNA 甲基化:对其再现性、可逆性及其与胎儿生长受限的关系的研究
- 批准号:
MR/P011799/1 - 财政年份:2017
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极高能伽马射线的天体物理学
- 批准号:
1707432 - 财政年份:2017
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$ 68.5万 - 项目类别:
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- 批准号:
ES/M009890/1 - 财政年份:2015
- 资助金额:
$ 68.5万 - 项目类别:
Research Grant
Advances of Methodology and Design for the Synthesis of Complex Polycyclic Natural Products
复杂多环天然产物的合成方法与设计进展
- 批准号:
1362561 - 财政年份:2014
- 资助金额:
$ 68.5万 - 项目类别:
Standard Grant
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