用尼卡匹定保护心肌-猫眼课题宝

用尼卡匹定保护心肌

批准号：

3920097

负责人：

M E MITCHELL

金额：

$0.0万

依托单位：

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/3920097

关键词：

cardiotonic agents heart arrest heart preservation laboratory rat myocardial ischemia /hypoxia nonhuman therapy evaluation

中文摘要

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英文摘要

To date approximately 50 rat hearts have been given cardioplegia containing nicardipine. It appears that nicardipine has a beneficial effect in protecting myocardium during ischemia at 37.5 degrees C, but not at 10 degrees C. The optimal dose of nicardipine for myocardial preservation has not yet been determined. These results are preliminary, and approximately 50 more animals will be required to complete the protocol.

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