胶体与晶体流体管理的效果。 -猫眼课题宝

胶体与晶体流体管理的效果。

批准号：

3920091

负责人：

M E MITCHELL

金额：

$0.0万

依托单位：

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/3920091

关键词：

body fluid balance therapy body fluid osmolarity colloids coronary bypass extracellular heart /lung bypass human subject human therapy evaluation liquid crystal postoperative complications postoperative state pulmonary edema respiratory function

中文摘要

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英文摘要

Forty adult patients undergoing elective surgical procedures requiring cardiopulmonary bypass will be studied in the perioperative period including the 24 hours immediately following operation. The hypotheses to be tested are: 1) measures of extravascular lung water and colloid osmotic pressure can be used to predict the postoperative clinical respiratory status of patients; and 2) the use of a colloid rather than a crystalloid solution for perioperative fluid resuscitation affects postoperative respiratory function and the need for respiratory support, hemodynamic variables, and cost. Possible adverse effects associated with either fluid resuscitation regimen will be determined.

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