AMINO ACID ANALYZER AND PROTEIN SEQUENCER

氨基酸分析仪和蛋白质测序仪

• 批准号: 3519852
• 负责人: Jay William FOX
• 金额: $ 7.9万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-04-04 至 1989-04-03
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3519852
• 关键词: aminoacid analyzer; biomedical automation; biomedical equipment purchase; high performance liquid chromatography; protein sequence

This request for a Shared Instrumentation Grant seeks funds for the purchase of an automated, high sensitivity amino acid analysis system and a protein/peptide sequencer. Use of these instruments will be shared by eight NIH grantees. These instruments will make available more rapid structural analyses of proteins and peptides; the data from which are an integral part and of great importance to the overall objectives of the investigations by these researchers. Currently, these analyses are being performed in the University of Virginia Protein and Nucleic Acid Research Facility. However, since this Facility serves researchers throughout the University as well as the Commonwealth, the instrument availability is totally saturated with sample turnover times of typically three to four weeks due to heavy demand. The eight investigators in this proposal realize the pressing need to expedite the production of structural data in order to maintain steady progress in their research programs. Thus, the requested instrumentation will play an important and necessary role in a large number of topically unrelated research projects, none of which would individually justify the purchase of such instrumentation. We hope to provide evidence showing the value of this instrumentation in the structural characterization of proteins and peptides as relevant to each researcher's needs.

此共享仪器补助金请求旨在为 购买自动化、高灵敏度氨基酸分析仪 系统和蛋白质/肽测序仪。 这些仪器的使用 将由 8 名 NIH 受资助者共享。 这些仪器将 提供更快速的蛋白质结构分析 肽；其中的数据是不可或缺的一部分并且具有重要意义 这些调查的总体目标的重要性 研究人员。 目前，这些分析正在 弗吉尼亚大学蛋白质和核酸研究设施。 然而，由于该设施为整个研究人员提供服务 大学以及英联邦，工具 样品周转时间已完全饱和 由于需求旺盛，通常需要三到四个星期。 八个 该提案中的调查人员意识到迫切需要加快速度 结构性数据生产保持平稳 他们的研究计划取得进展。 因此，所要求的 仪器仪表将发挥重要且必要的作用 大量主题不相关的研究项目，没有一个 这将单独证明购买此类产品的合理性 仪器仪表。 我们希望提供证明价值的证据 该仪器在结构表征中的应用 与每个研究人员的需求相关的蛋白质和肽。