PROTEIN SEQUENCER/AMINO ACID ANALYZER

蛋白质测序仪/氨基酸分析仪

• 批准号: 3519907
• 负责人: DAVID W. SPEICHER
• 金额: $ 7.3万
• 依托单位: WISTAR INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-04-01 至 1989-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3519907
• 关键词: aminoacid analyzer; biomedical equipment purchase; high performance liquid chromatography; hydrolysis; protein sequence

The acquisition of a pulsed liquid phase protein sequencer, high sensitivity amino acid analyser and a microbore HPLC is proposed to equip a centralized protein chemistry laboratory in the Wistar Institute. This equipment will be vitally important for at least 17 projects which are described in this proposal. In several cases specific projects represent the protein chemistry needs of relatively large research groups and these 17 projects will therefore directly or indirectly benefit the research efforts of about half of the 80 professional scientific research staff members of the Wistar Institute. Acquisition of this equipment is part of a major commitment of this institute to develop a modern fully equipped facility which can provide essential protein chemistry services and collaborative resources to diverse biomedical problems. The facility will be largely self-sustaining via charge backs to investigators after the first year. It will be available to all potential users at the Wistar Institute with priority given to the user groups described in this proposal. The P.I. of this proposal will assume direct administrative and scientific responsibility of the facility. An internal Advisory Committee comprised of users and administrative officials will aid in establishing priorities and policies to ensure maximum utilization of this resource. The administration of the Wistar Institute has allocated space and has made the necessary staff commitments for efficient establishment of this facility. The Institute is also committed to maintaining these instruments for their useful lifetime.

获得了脉冲液相蛋白质测序仪， 提出了一种灵敏度高的氨基酸分析仪和微孔高效液相色谱仪 在Wistar实验室里建立一个集中的蛋白质化学实验室， 院 这些设备对至少17个国家来说至关重要。 本提案中所述的项目。 在若干情况下 具体的项目代表了蛋白质化学的需求， 相对较大的研究群体，这十七个项目， 因此，直接或间接地受益于研究工作， 80名专业科研人员中约有一半 Wistar Institute的成员。 购置这些设备是 该研究所的一个主要承诺的一部分，发展一个现代化的 设备齐全的设施，可提供必需的蛋白质 化学服务和协作资源， 生物医学问题。 该设施将主要通过收费来自我维持， 第一年后的调查。 它将提供给所有人 Wistar研究所的潜在用户，优先考虑 本提案中所述的用户群。 私家侦探本提议的 将承担直接的行政和科学责任， 设施。 由用户组成的内部咨询委员会 和行政官员将帮助确定优先事项， 确保最大限度地利用这些资源。 的 Wistar研究所的管理部门已经分配了空间， 作出必要的工作人员承诺， 建立这个设施。 研究所还致力于 维护这些仪器的使用寿命。