3D Cryo-FIBSEM Imaging Facility for Biological and Material Sciences.

用于生物和材料科学的 3D Cryo-FIBSEM 成像设备。

• 批准号: LE150100132
• 负责人: A/Prof Georg Ramm
• 金额: $ 57.34万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-02-02 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE150100132
• 关键词: 3D; Cryo; FIBSEM; Imaging; Facility

3D Cryo-FIBSEM imaging facility for biological and material sciences: The Cryo-Focused Ion Beam Scanning Electron Microscope (Cryo-FIBSEM) will reveal isometric 3D information on the structure and composition of specimens at the nanometre scale. The cryo-FIBSEM will be the first instrument of this type in Australia able to operate in a low temperature cryogenic mode. This will enable the imaging of vitrified biological materials in a near native state and of non-biological material to allow imaging of, for example, fluids, emulsions, gels and interfaces between biological and non-biological materials. Synergistic workflows incorporating unique high-end microscopes will enable the study of complex biological structures in their native context and atomic scale imaging of beam sensitive materials.

用于生物和材料科学的3D Cryo-FIB SEM成像设备：Cryo-Focused Ion Beam Scanning Electron Microscope（Cryo-FIB SEM）将揭示纳米级样品结构和成分的等距3D信息。cryo-FIBSEM将是澳大利亚第一台能够在低温低温模式下运行的此类仪器。这将使得能够对处于接近天然状态的玻璃化生物材料和非生物材料进行成像，以允许对例如流体、乳液、凝胶和生物材料与非生物材料之间的界面进行成像。结合独特的高端显微镜的协同工作流程将使复杂的生物结构的研究在其原生环境和原子尺度成像的光束敏感材料。