New generation direct electron detector for cryo-electron microscopy

用于冷冻电子显微镜的新一代直接电子探测器

• 批准号: LE200100045
• 负责人: A/Prof Georg Ramm
• 金额: $ 41.54万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-06-30 至 2021-06-15
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE200100045
• 关键词: New; generation; direct; electron; detector

This Project aims to generate urgently needed capabilities for cryo elctron microscopy through the newest generation direct electron detector, the Gatan K3 camera. This project expects to generate highest resolution molecular structures of biological and non-biological materials including pharmacological targets, nanomaterials, and other electron beam-sensitive materials. Expected outcomes are high impact discoveries, training opportunities, international collaborations, and publications addressing fundamental questions in biology and pharmaceutical science. This should provide significant benefits in wide ranging areas of nanotechnology, pharmacy, renewable energy, and agriculture.

该项目旨在通过最新一代的直接电子探测器Gatan K3相机产生急需的低温电子显微镜功能。该项目预计将生成生物和非生物材料的最高分辨率分子结构，包括药理学靶标，纳米材料和其他电子束敏感材料。预期成果是高影响力的发现，培训机会，国际合作和出版物，解决生物学和制药科学的基本问题。这将为纳米技术、制药、可再生能源和农业等广泛领域带来重大利益。