A fibroin-based prosthetic Bruch's membrane for the treatment of age-related macular degeneration

基于丝素蛋白的人工布鲁赫膜用于治疗年龄相关性黄斑变性

• 批准号: nhmrc : GNT1080302
• 负责人: A/Pr Nigel Barnett
• 金额: $ 51.92万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/fibroin-based-prosthetic-macular-degeneration/1345345
• 关键词: fibroin; based; prosthetic; Bruch; membrane

Our aim is to develop a new therapy for the treatment of patients with age-related macular degeneration (AMD), a leading cause of blindness in our ageing population. The novelty of our therapy resides in using a protein derived from silk fibers (fibroin), to rebuild a healthy barrier between the outermost layer of the retina and adjacent blood vessels. We expect that the findings from this study will eventually lead to better outcomes for patients with AMD.

我们的目标是开发一种治疗老年性黄斑变性（AMD）患者的新疗法，AMD是老年人失明的主要原因。我们疗法的新奇在于使用一种来自丝纤维的蛋白质（丝心蛋白），在视网膜最外层和相邻血管之间重建健康的屏障。我们希望这项研究的结果最终能为AMD患者带来更好的结果。