Type 2 diabetes in childhood: building a platform to support novel intervention strategies

儿童肥胖的增加导致儿童患上与肥胖相关的2型糖尿病，这在20年前的英国是从未见过的。我们知道这些孩子成年后会患上严重的心血管疾病；但我们不知道预防或延缓这些疾病发病的最佳治疗方法是什么。这项建议是建立一个英国国家2型糖尿病儿童队列，仔细描述，以便他们可以参与治疗的临床试验，以改善他们的结果。

The rise in childhood obesity has led to children developing obesity related type 2 diabetes, something that was never seen in the UK 20 years ago. We know that these children will get serious cardiovascular disease in adulthood; but we do not know what are the best treatments to prevent or delay the onset to these diseases. This proposal is to establish a UK national cohort of children with type 2 diabetes, carefully characterised, so that they can be involed in clinical trials of treatments to improve their outcomes.