ARRAY PROCESSOR
阵列处理器
基本信息
- 批准号:3519641
- 负责人:
- 金额:$ 14.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1987
- 资助国家:美国
- 起止时间:1987-04-01 至 1988-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This proposal seeks funds for the acquisition of a 64-bit array
processor to be used in conjunction with an existing 32-bit
minicomputer. Projects in four subject areas will benefit from
access to such a high speed computational capability. The four
projects are: 1) a simulation of the urinary concentrating
mechanism in the renal medulla. Previous simulations have
fallen short of predicting the performance achieved by
laboratory animals; this project seeks to improve performance by
incorporating known membrane transport parameters into a more
realistic model of medullary anatomy. The simulation will
require the solution of a large non-linear boundary value
problem. 2a) a syntactic model of glycogen metabolism in liver
and muscle. Compartment models based on radioactive tracer
data have failed to deal with recycling of tracer molecules, and
also with the difficulty of predicting the incorporation of tracer
into glycogen, a large polysaccharide molecule with a preferred
order of glucose incorporation and removal. Syntactic modelling
keeps track of each carbon atom in each molecule as it
progresses through the metabolic pathways. 2b) A minimal
model of body glucose and insulin dynamics has been used in
human beings to aid in the early diagnosis of diabetes mellitus;
the method depends on measuring the response to a standard
forcing by injecting glucose. The success of the approach now
requires the design of optimal strategies for both injection and
sampling protocols. 3) The Na-K-ATPase is an ubiquitous
transport enzyme which has come to occupy a central place in
most schemes of cellular electrolyte transport and cell volume
regulation. Complete amino acid sequence information is
available for this protein, but understanding the mechanism of
transport and of energy transduction requires the determination
of secondary and tertiary protein structure. An attempt will be
made to simulate these structures from the known sequences. 4)
Experimental evidence suggests that the semicircular canal
cupula of the vestibular apparatus in the guitarfish acts as a
pressure sensitive membrane with site specific response
characteristics related to the dynamics of the stimulus. This
hypothesis can be evaluated by a finite element analysis that
includes temporally as well as spatially dependent variables.
该提案为购买64位阵列寻求资金
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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DONALD J MARSH其他文献
DONALD J MARSH的其他文献
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{{ truncateString('DONALD J MARSH', 18)}}的其他基金
MODELING OF NON LINEAR DYNAMICS OF RENAL AUTOREGULATION
肾脏自动调节的非线性动力学建模
- 批准号:
6611238 - 财政年份:2002
- 资助金额:
$ 14.1万 - 项目类别:
MODELING OF NON LINEAR DYNAMICS OF RENAL AUTOREGULATION
肾脏自动调节的非线性动力学建模
- 批准号:
6480874 - 财政年份:2001
- 资助金额:
$ 14.1万 - 项目类别:
MODELING OF NON LINEAR DYNAMICS OF RENAL AUTOREGULATION
肾脏自动调节的非线性动力学建模
- 批准号:
6205814 - 财政年份:1999
- 资助金额:
$ 14.1万 - 项目类别:
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