MRC-University of Glasgow Centre for Virus Research

MRC-格拉斯哥大学病毒研究中心

• 批准号: G0801822/1
• 负责人: Massimo Palmarini
• 金额: $ 820.52万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0801822%2F1
• 关键词: MRC; University; Glasgow; Centre; Virus

The purpose of the application is to build a new internationally recognised centre for research on virology. The Medical Research Council?s highly rated Virology Unit in Glasgow will be re-housed in a new state-of-the-art building within the University of Glasgow?s Institute of Comparative Medicine on the Garscube Campus to form the Centre for Integrated Virology (CIV). This new organisation will address the challenges presented by viruses in the 21st century by bringing together a unique array of experts with many years of research experience on some of the most important viral agents that threaten human health today. Viruses represent a very diverse range of agents that continue to exert a major burden on human health as causes of chronic infection leading to diseases including hepatitis, AIDS and cancer. Viruses also cause acute, life-threatening infections such as pneumonia or encephalitis and present a challenge to control by vaccines due to their ability to change rapidly and hence evade detection and destruction by our immune systems before causing serious disease. The ability of some viruses to jump from one species to another is of particular concern and presents the threat of new world-wide epidemics. On the other hand, viruses can be used as tools in biology and medicine as they can enrich our understanding of biology at the cellular level and can even be used to deliver therapies for genetic diseases and to kill cancer cells in patients. By integrating these aspects of virology and bringing clinicians and human virus experts alongside pathologists and scientists focusing on animal viruses and the mathematical analysis of viral epidemics, the CIV will provide added value and a unique strategic resource for the UK. The CIV will also respond to the acknowledged need for improved training and career development opportunities for the next generation of clinicians, veterinarians and scientists who will in future carry the responsibility for the control of viruses and other infectious agents.

申请的目的是建立一个新的国际公认的病毒学研究中心。格拉斯哥的医学研究委员会-S高度评价的病毒学单位将被重新安置在格拉斯哥大学S比较医学研究所内的一栋新建筑内，以形成综合病毒学中心(CIV)。这个新的组织将通过汇聚一批独特的专家，在当今威胁人类健康的一些最重要的病毒制剂方面拥有多年的研究经验，来应对病毒在21世纪带来的挑战。病毒代表着各种各样的病原体，作为导致肝炎、艾滋病和癌症等疾病的慢性感染的原因，继续对人类健康造成重大负担。病毒还会引起肺炎或脑炎等危及生命的急性感染，并对疫苗的控制构成挑战，因为它们能够迅速变化，从而在造成严重疾病之前躲避我们的免疫系统的检测和破坏。一些病毒从一个物种跳到另一个物种的能力尤其令人担忧，并构成了新的全球流行病的威胁。另一方面，病毒可以作为生物学和医学的工具，因为它们可以在细胞水平上丰富我们对生物学的理解，甚至可以用来提供遗传疾病的治疗方法和杀死患者的癌细胞。通过整合病毒学的这些方面，并将临床医生和人类病毒专家与专注于动物病毒和病毒流行的数学分析的病理学家和科学家一起聚集在一起，CIV将为英国提供附加值和独特的战略资源。CIV还将回应公认的需要，即为下一代临床医生、兽医和科学家提供更好的培训和职业发展机会，他们将在未来承担控制病毒和其他传染病的责任。