TREATMENT OF MALIGNANT BRAIN TUMORS WITH INTERSTITIAL RADIOTHERAPY

尽管多模式治疗具有攻击性，但中位数 高级别胶质瘤，特别是多形性胶质母细胞瘤的存活率较低 一年多，治愈一般都是轶事。这些肿瘤通常 超过了完全手术切除的限度和剂量的 传统的外放射治疗受到周围环境的限制。 大脑耐受性。通过将放射性的碘125种子直接放入 在肿瘤床上，我们可以实现对肿瘤的高辐射剂量，在 辐射对周围正常大脑的急剧下降，从而 通过以低剂量率去杠杆化来实现更高的治疗比率。

Despite multi-modality treatment of an aggressive nature, the median survival in high-grade gliomas, especially glioblastoma multiforme is less than a year, and cure is generally anecdotal. These tumors have usually extended beyond the limits of a complete surgical resection and a dose of conventional external beam radiotherapy has been limited by surrounding brain tolerance. By placing radioactive seeds of Iodine 125 directly into the tumor bed, we can achieve a high radiation dose to the tumor, at a sharp fall-off of radiation to the surrounding normal brain, and thereby achieve an increased therapeutic ratio by delevering at low dose rates.