课题基金 / 基金详情

DISPOSITION OF XENOBIOTICS

DISPOSITION OF XENOBIOTICS
异生物质的处置
批准号：
4693160
负责人：
L S BIRNBAUM
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4693160
关键词：
drug administration routes drug adverse effect drug metabolism toxin metabolism

项目摘要

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L S BIRNBAUM的其他基金

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中文摘要
翻译
药代动力学因子可以极大地帮助剂量设定
英文摘要
Pharmacokinetic factors can assist greatly in both dose-setting for toxicity studies and in interpretation of the results. Chemicals on-test by the NTP are nominated for disposition studies. The absorpiton (oral, dermal), distribution, metabolism, and excretion is studied in rats and other species as needed. The effect of dose is determined. In this way, the effects of chronic exposure may be predicted. The first chemicals to be studied in this project include o-benzyl-p-chlorophenol (BCP), and citral (oil of lemon).
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会议论文
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DISPOSITION OF XENOBIOTICS
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