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KINETICS OF CALCIUM METABOLISM IN CHILDHOOD

KINETICS OF CALCIUM METABOLISM IN CHILDHOOD
儿童期钙代谢动力学
批准号:
4693762
负责人:
J B SIDBURY
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
这项研究利用两种不同的稳定钙同位素来确定 钙动力学。事实上,这些同位素是非放射性的,它们可以 可用于儿童和孕妇。给出了一种同位素 一种是静脉注射,另一种是口服。因为这些同位素具有不同的 原子量,这两种钙可以在质谱仪中测定。 同时。采血只需12小时。尿液 每8小时连续收集一次,持续2周。使用 由Mones Berman博士设计的建模程序,可以确定大小 在几个钙池中。 这项研究已经被修改,包括对怀孕和哺乳的研究 女人。我们的课题是在第三个月的时候学习的。 哺乳期和哺乳期6个月后重复研究 结束了。 Prader-Willi综合征与遗传成分有关, 为改变新陈代谢和未来的钙平衡研究提供证据。
英文摘要
The study utilizes two different stable isotopes of calcium to determine calcium kinetics. The fact that the isotopes are non-radioactive, they can be used in children and pregnant women. One isotope is given intravenously, the other by mouth. Since the isotopes have different atomic weights, the two calciums can be determined in the mass spectrometer simultaneously. Blood sampling is required for 12 hours only. Urine collections are made continuously every 8 hours for 2 weeks. Using the modeling program designed by Dr. Mones Berman, one can determine the size of the several calcium pools. The study had been amended to include the study of pregnant and lactating women. Our subject has been studied in the third trimester, during lactation and the study will be repeated 6 months after lactation has concluded. The Prader-Willi Syndrome continues in relation to the genetic components, evidense for altered metabolism and in the future calcium balance studies.
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会议论文
GLYCOGEN STORAGE DISEASE
EVALUATION OF NALMEFENE, AN ENDORPHIN ANTAGONIST, IN THE CONTROL OF APPETITE
GLYCOGEN STORAGE DISEASE
METABOLISM IN CHILDREN WITH GLYCOGEN STORAGE DISEASE, TYPE I
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