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INVOLVEMENT OF CALCIUM, FODRIN, AND GLUTAMATE IN SEIZURES

INVOLVEMENT OF CALCIUM, FODRIN, AND GLUTAMATE IN SEIZURES
钙、卵黄蛋白和谷氨酸与癫痫发作有关
批准号:
4696978
负责人:
S NADI
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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中文摘要
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英文摘要
The work will involve the study of epileptic foci and the evaluation of the status of glutamate receptors, the cytoskeletal protein fodrin and the flux of calcium ions. The epileptic seizure has been demonstrated to occur as a result of a shift of external calcium ions to the interior of the cell. Since calcium ions are also known to activate calpain, which degrades fodrin, which is responsible for maintaining the integrity of the membrane. The question of interest in this study is to determine whether fodrin breakdown is directly linked to the spread of epileptic activity.
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会议论文
MECHANISMS OF KINDLED SEIZURE SUPPRESSION BY CYSTEAMINE
MOLECULAR BIOLOGIC BASIS OF KINDLING
STUDIES OF HUMAN EPILEPTIC FOCUS
INVESTIGATIONS OF ATPASE AND OUABAIN-LIKE FACTOR IN EPILEPSY
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海外基金
Piezo1/Cytoskeleton介导的YAP核易位在4D仿生骨膜修复骨缺损中的作用及机制研究
  • 批准号:
    --
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    30万元
  • 批准年份:
    2022
  • 负责人:
    游东奇
  • 依托单位: