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INVOLVEMENT OF ABNORMALITIES IN GLUTAMATE DECARBOXYLASE GENE IN KINDLED RAT

INVOLVEMENT OF ABNORMALITIES IN GLUTAMATE DECARBOXYLASE GENE IN KINDLED RAT
点燃大鼠谷氨酸脱羧酶基因异常的涉及
批准号：
3969087
负责人：
S NADI
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3969087
关键词：
decarboxylases epilepsy glutamates human subject inborn metabolism disorder messenger RNA

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中文摘要
翻译
据报道，氨基丁酸的各个步骤都出现了异常。 出现在癫痫中。本研究的目的是研究 谷氨酸脱羧酶(GAD)基因原位杂交研究 假手术大鼠。预计这种方法将表明，如果 有无癫痫样活动所致的mRNA改变。这是一项研究 目前正在进行；目前还没有结果。
英文摘要
Abnormalities in various steps of the aminobutyric acid have been reported to occur in epilepsy. The aim of the present study is to study the glutamate decarboxylase (GAD) gene by in situ hybridization in kindled and sham operated rats. It is anticipated that this approach will show if there are any mRNA changes due to epileptiform activity. This is a study currently being undertaken; no results are available yet.
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会议论文
MECHANISMS OF KINDLED SEIZURE SUPPRESSION BY CYSTEAMINE
INVOLVEMENT OF CALCIUM, FODRIN, AND GLUTAMATE IN SEIZURES
MOLECULAR BIOLOGIC BASIS OF KINDLING
STUDIES OF HUMAN EPILEPTIC FOCUS
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