Establishment of a National Network on Musculoskeletal Ageing

我们的总体目标是建立一个新的国家网络，通过确定：关键易处理的研究优先事项，支持肌肉骨骼老化研究能力和战略的一步变化;发展一个综合的多学科小组，以解决已确定的研究差距;提供一个平台，传播最佳实践;支持早期职业研究人员（ECR）建立研究能力，并确保目前UKRI投资的寿命;并协调正在进行的创新研究计划，以确定，开发和转化我们的发现科学的临床影响的发现。至关重要的是，该网络将通过确定老年人保持流动性的方法，为实现政府到2035年再独立生活5年的“大挑战”目标做出贡献。该网络将汇集三个主要申请人的科学专长。专注于骨，肌肉和关节的主要慢性非传染性疾病（骨质疏松症，肌肉减少症，类风湿性关节炎和骨关节炎），这些团体的整合将激发一个真正的板凳到床边的方法，为卫生政策提供强有力的证据基础，支持英国肌肉骨骼老化研究能力/能力的一步变化，并促进健康寿命的增加。

Our overall aim is to establish a new national network which will underpin a step change in musculoskeletal ageing research capacity and strategy, by identifying: key tractable research priorities; developing an integrated multi-disciplinary grouping to address the identified research gaps; providing a platform to disseminate best practice; supporting Early Career Researchers (ECRs) to build research capacity and ensure longevity to current UKRI investments; and coordinating an ongoing programme of innovative studies to identify, develop and translate findings from our discovery science to clinical impact. Crucially the network will contribute to delivering the government “Grand Challenge” target of 5 more years of independent living by 2035, by identifying approaches to maintain mobility in old age. The network will bring together the scientific excellence of the three principal applicants. Focusing on the leading chronic non-communicable disorders of bone, muscle and joint (osteoporosis, sarcopenia, rheumatoid arthritis and osteoarthritis), the integration of these groups will galvanize a truly bench to bedside approach to provide a strong evidence base for health policy, underpinning a step change in UK musculoskeletal ageing research capability/capacity, and promoting increased healthspan.