A Network for Studying Psychological Resilience in Low and Middle-Income Countries (NESP)
低收入和中等收入国家心理弹性研究网络 (NESP)
基本信息
- 批准号:MC_PC_MR/R01910X/1
- 负责人:
- 金额:$ 24.03万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2018
- 资助国家:英国
- 起止时间:2018 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Vulnerability to or resilience to the commonest mental health disorders (depression, anxiety, drug and alcohol misuse) is related to the combination of genetic susceptibility, early life factors and an individual's current environment. Studies, over 95% of which have been confined to high income countries (HICs), have confirmed the importance of genes, development and adult environment. However, very little is known of these factors in low and middle-income countries (LMICs), where the burden of such common mental health disorders is even more substantial than in HICs.Here we propose a powerful network of global leaders to analyse the key factors in three contrasting LMIC settings in three regions of the world, Nepal, Malawi and Costa Rica. This will enable us systematically to determine the processes leading to vulnerability or resilience to common disorders of mental health and exploit this knowledge, enabled by globally-leading data sciences and within-country expertise, to develop specific approaches to reinforce resilience and support prevention, diagnosis and treatment.Our approach is highly multidisciplinary, combining genetic, clinical and social sciences expertise to provide a comprehensive view of an individual's genetics, development and environment. We will combine this expertise with world-leading informatics capacity to create a network for the study of psychological resilience across diverse environments and economies.
对最常见的精神健康疾病(抑郁、焦虑、药物和酒精滥用)的脆弱性或恢复力与遗传易感性、早期生活因素和个人当前环境的结合有关。超过 95% 的研究仅限于高收入国家 (HIC),这些研究证实了基因、发育和成人环境的重要性。然而,人们对低收入和中等收入国家 (LMIC) 的这些因素知之甚少,这些国家中此类常见精神健康疾病的负担甚至比高收入国家还要严重。在此,我们提议建立一个强大的全球领导人网络,以分析世界三个地区(尼泊尔、马拉维和哥斯达黎加)三个截然不同的 LMIC 环境中的关键因素。这将使我们能够系统地确定导致常见心理健康疾病的脆弱性或复原力的过程,并利用全球领先的数据科学和国内专业知识支持的这些知识,开发增强复原力并支持预防、诊断和治疗的具体方法。我们的方法是高度多学科的,结合遗传、临床和社会科学专业知识,提供对个人遗传、发育的全面了解。 和环境。我们将把这些专业知识与世界领先的信息学能力相结合,创建一个研究跨不同环境和经济体的心理弹性的网络。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Research Handbook on the Sociology of Law
法律社会学研究手册
- DOI:10.4337/9781789905182.00014
- 发表时间:2020
- 期刊:
- 影响因子:0
- 作者:Cloatre E
- 通讯作者:Cloatre E
Using a knowledge exchange event to assess study participants' attitudes to research in a rapidly evolving research context.
- DOI:10.12688/wellcomeopenres.15651.1
- 发表时间:2020-01-01
- 期刊:
- 影响因子:0
- 作者:Beange, Iona;Kirkham, Elizabeth J;McIntosh, Andrew M
- 通讯作者:McIntosh, Andrew M
Evaluating the Brain Disease Model of Addiction
评估成瘾的脑疾病模型
- DOI:10.4324/9781003032762-30
- 发表时间:2022
- 期刊:
- 影响因子:0
- 作者:Barnett A
- 通讯作者:Barnett A
Predictors of emotional problems in 5-year-old children: an international comparison between two cohorts in Chile and Scotland
- DOI:10.1007/s12144-020-01336-5
- 发表时间:2021-02-05
- 期刊:
- 影响因子:2.8
- 作者:Farkas, Chamarrita;Girard, Lisa-Christine;MacBeth, Angus
- 通讯作者:MacBeth, Angus
The benefits, costs and feasibility of a low incidence COVID-19 strategy.
- DOI:10.1016/j.lanepe.2021.100294
- 发表时间:2022-03
- 期刊:
- 影响因子:0
- 作者:Czypionka T;Iftekhar EN;Prainsack B;Priesemann V;Bauer S;Calero Valdez A;Cuschieri S;Glaab E;Grill E;Krutzinna J;Lionis C;Machado H;Martins C;Pavlakis GN;Perc M;Petelos E;Pickersgill M;Skupin A;Schernhammer E;Szczurek E;Tsiodras S;Willeit P;Wilmes P
- 通讯作者:Wilmes P
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Andrew McIntosh其他文献
MP67-14 WHITE BLOOD CELL COUNT AT DISCHARGE FOLLOWING RADICAL CYSTECTOMY ASSOCIATES WITH RISK FOR READMISSION
- DOI:
10.1016/j.juro.2015.02.2497 - 发表时间:
2015-04-01 - 期刊:
- 影响因子:
- 作者:
Philip Abbosh;Timothy Ito;Jason Mannion;Andrew McIntosh;Mark Dziemianowicz;Nikhil Waingankar;Mohammed Haseebuddin;David Chen;Richard Greenberg;Rosalia Viterbo;Alexander Kutikov;Robert Uzzo;Marc Smaldone - 通讯作者:
Marc Smaldone
PD59-05 ACTIVE SURVEILLANCE FOR RENAL MASSES WITH > 5 YEARS OF FOLLOW-UP: TUMOR GROWTH, DELAYED INTERVENTION RATES, AND CLINICAL OUTCOMES
- DOI:
10.1016/j.juro.2017.02.2633 - 发表时间:
2017-04-01 - 期刊:
- 影响因子:
- 作者:
Andrew McIntosh;Pranav Parikh;Anthony Tokarski;Eric Ross;David Chen;Richard Greenberg;Alexander Kutikov;Marc Smaldone;Rosalia Viterbo;Robert Uzzo - 通讯作者:
Robert Uzzo
94. EXAMINING TARGETABLE PATHWAYS BETWEEN GENETIC RISK FOR DEPRESSION AND ADOLESCENT ONSET DEPRESSION: THE MEDIATING ROLE OF ADVERSE CHILDHOOD EXPERIENCES
- DOI:
10.1016/j.euroneuro.2021.07.180 - 发表时间:
2021-10-01 - 期刊:
- 影响因子:
- 作者:
Alex Kwong;Jessie Baldwin;Varun Warrier;Reut Avinun;Tugce Melisa Chuong;Hannah Jones;Hannah Sallis;Rebecca Pearson;Andrew McIntosh - 通讯作者:
Andrew McIntosh
W34. BIAS IN THE USE OF POLYGENIC SCORES TO EXPLORE GENETIC NURTURING EFFECTS IN BIOLOGICAL PARENT-OFFSPRING TRIOS
- DOI:
10.1016/j.euroneuro.2021.08.122 - 发表时间:
2021-10-01 - 期刊:
- 影响因子:
- 作者:
Tugce Melisa Chuong;Carmen Amador;Mark Adams;Alex Kwong;Hannah Sallis;Rebecca Pearson;Andrew McIntosh;Chris S. Haley - 通讯作者:
Chris S. Haley
A GENOME-WIDE META-ANALYSIS OF TREATMENT-RESISTANT DEPRESSION DEFINED USING ELECTRONIC HEALTH RECORDS
- DOI:
10.1016/j.euroneuro.2022.07.300 - 发表时间:
2022-10-01 - 期刊:
- 影响因子:
- 作者:
Chiara Fabbri;Kristi Krebs;Julia Sealock;Brittany Mitchell;Andrew McIntosh;Kelli Lehto;Lili Milani;Cathryn Lewis - 通讯作者:
Cathryn Lewis
Andrew McIntosh的其他文献
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{{ truncateString('Andrew McIntosh', 18)}}的其他基金
Generation Malawi: A study of family, maternal and childhood mental health
马拉维一代:家庭、孕产妇和儿童心理健康研究
- 批准号:
MR/S035818/1 - 财政年份:2019
- 资助金额:
$ 24.03万 - 项目类别:
Research Grant
Leveraging routinely collected and linked research data to study the causes and consequences of common mental disorders
利用定期收集和链接的研究数据来研究常见精神障碍的原因和后果
- 批准号:
MC_PC_17209 - 财政年份:2018
- 资助金额:
$ 24.03万 - 项目类别:
Intramural
Modelling psychosis using DISC1 human induced pluripotent stem cells
使用 DISC1 人类诱导多能干细胞模拟精神病
- 批准号:
MR/J004367/1 - 财政年份:2012
- 资助金额:
$ 24.03万 - 项目类别:
Research Grant
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