Disorders of attention, awareness and cognitive control

注意力、意识和认知控制障碍

• 批准号: MC_UU_00030/11
• 负责人: Tom Manly
• 金额: $ 273.7万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MC_UU_00030%2F11
• 关键词: Disorders; attention; awareness; cognitive; control

Each year, millions of people around the world suffer an acquired brain injury (ABI). This could be in a road accident, an armed conflict, or from a tumour or stroke. ABIs are the single biggest cause of long-term disability in countries such as the UK and have a high cost for individuals, families and economies. ABIs can have many consequences. Among the most common are problems in cognition (e.g. memory and attention) and mood. This programme is focused on better understanding these difficulties, how they interact, and what they can tell about normal function. It also aims, through this improved understanding, to develop better clinical assessments and practical rehabilitation treatments. Examples include; a) investigating how we move from one activity to another and whether impairments in the necessary processes help us to understand some of the problems faced by people with ABI; b) looking at the relationships between problems in planning and overall activity levels and whether tackling both can improve mood; and c) whether we can develop improved assessments for common post-ABI impairments in spatial awareness and use these to test new treatments.

每年，全世界有数百万人遭受后天脑损伤(ABI)。这可能是在交通事故、武装冲突、肿瘤或中风中。在英国等国家，艾滋病是导致长期残疾的最大原因，对个人、家庭和经济都有很高的成本。艾比斯可能会产生很多后果。其中最常见的是认知(例如记忆和注意力)和情绪方面的问题。这个项目的重点是更好地理解这些困难，它们是如何相互作用的，以及它们可以告诉我们什么是正常的功能。它还旨在通过这种更好的理解，开发更好的临床评估和实用的康复治疗。例子包括：a)调查我们如何从一项活动转移到另一项活动，以及必要过程中的损伤是否有助于我们理解ABI患者面临的一些问题；b)查看计划中的问题与整体活动水平之间的关系，以及处理两者是否可以改善情绪；c)我们是否可以对ABI后常见的空间意识障碍进行改进评估，并利用这些评估来测试新的治疗方法。

项目成果

Mood, Activity Participation, and Leisure Engagement Satisfaction (MAPLES): results from a randomised controlled pilot feasibility trial for low mood in acquired brain injury.

• DOI: 10.1186/s12916-023-03128-7
• 发表时间: 2023-11-16
• 期刊: BMC MEDICINE
• 影响因子: 9.3
• 作者: Kusec, Andrea;Murphy, Fionnuala C.;Peers, Polly V.;Bennett, Ron;Carmona, Estela;Korbacz, Aleksandra;Lawrence, Cara;Cameron, Emma;Bateman, Andrew;Watson, Peter;Allanson, Judith;Dutoit, Pieter;Manly, Tom
• 通讯作者: Manly, Tom

Segregation and integration of the functional connectome in neurodevelopmentally 'at risk' children.

• DOI: 10.1111/desc.13209
• 发表时间: 2022-05
• 期刊: Developmental science
• 影响因子: 3.7
• 作者: Jones JS;CALM Team;Astle DE
• 通讯作者: Astle DE

Measuring Intolerance of Uncertainty After Acquired Brain Injury: Factor Structure, Reliability, and Validity of the Intolerance of Uncertainty Scale-12.

获得性脑损伤后测量不确定性的不耐受性：不确定性不耐受量表 12 的因子结构、可靠性和有效性。

• DOI: 10.1177/10731911231182693
• 发表时间: 2023
• 期刊: Assessment
• 影响因子: 3.8
• 作者: Kusec A

Emotional mental imagery generation during spontaneous future thinking: relationship with optimism and negative mood.

自发未来思考过程中情绪心理意象的产生：与乐观和消极情绪的关系。

• DOI: 10.1007/s00426-021-01501-w
• 发表时间: 2022
• 期刊: Psychological research
• 作者: Ji JL

Imagine How Good That Feels: The Impact of Anticipated Positive Emotions on Motivation for Reward Activities

• DOI: 10.1007/s10608-022-10306-z
• 发表时间: 2022-05
• 期刊: Cognitive Therapy and Research
• 影响因子: 2.8
• 作者: Max Heise;J. Werthmann;F. Murphy;B. Tuschen-Caffier;Fritz Renner