Chronic Diseases and Urban Health incorporating the TB case-control platform

慢性病和城市健康纳入结核病病例控制平台

• 批准号: MC_UU_00031/6
• 负责人: Jayne Sutherland
• 金额: $ 256.8万
• 依托单位: London School of Hygiene & Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MC_UU_00031%2F6
• 关键词: Chronic; Diseases; Urban; Health; incorporating

Changes in environment, nutrition, infrastructure, and epidemics has had profound impacts on the health of people worldwide. The impact in developing countries is even more pronounced due to lack of adequate health systems. The TB platform has demonstrated the importance of active cases finding, monitoring, follow up and analysis of exposed contacts on the overall health of the population. The evolution of the platform to chronic diseases and urban health will allow us to upscale this work and better evaluate the requirements for disease monitoring and prevention in The Gambia. The Chronic Diseases and Urban Health platform will support the planned work on non-communicable diseases and emerging health risks for the Unit. Information will be collected on environment, socio-economic status and risk factors related to lifestyle and will therefore work as a ‘targeted’ urban health surveillance system.

环境、营养、基础设施和流行病的变化对全世界人民的健康产生了深远影响。由于缺乏适当的卫生系统，发展中国家受到的影响更为明显。结核病平台已经证明了发现、监测、跟踪和分析活动病例以及接触者对人口整体健康的重要性。该平台向慢性病和城市健康的发展将使我们能够扩大这项工作，并更好地评估冈比亚疾病监测和预防的要求。慢性病和城市卫生平台将支持该股计划开展的关于非传染性疾病和新出现的健康风险的工作。将收集有关环境、社会经济状况和与生活方式有关的风险因素的信息，因此将作为一个“有针对性的”城市健康监测系统。

项目成果

The impact of prior SARS-CoV-2 infection on host inflammatory cytokine profiles in patients with TB or other respiratory diseases.

• DOI: 10.3389/fimmu.2023.1292486
• 发表时间: 2023
• 期刊: Frontiers in immunology
• 影响因子: 7.3

Diagnostic performance of host protein signatures as a triage test for active pulmonary TB.

• DOI: 10.1128/jcm.00264-23
• 发表时间: 2023-10-24
• 期刊: JOURNAL OF CLINICAL MICROBIOLOGY
• 影响因子: 9.4
• 作者: Koeppel, Lisa;Denkinger, Claudia M.;Wyss, Romain;Broger, Tobias;Chegou, Novel N.;Dunty, Jill M.;Scott, Kerry;Caceres, Tatiana;Dutoit, Elloise;Ugarte-Gil, Cesar;Nicol, Mark;Gotuzzo, Eduardo;Corstjens, Paul L. A. M.;Geluk, Annemieke;Sutherland, Jayne;Sigal, George B.;Moreau, Emmanuel;Albertini, Audrey;Mantsoki, Anna;Ongarello, Stefano;Walzl, Gerhard;Fernandez Suarez, Marta
• 通讯作者: Fernandez Suarez, Marta

Neutrophils Contribute to Severity of Tuberculosis Pathology and Recovery From Lung Damage Pre- and Posttreatment.

• DOI: 10.1093/cid/ciab729
• 发表时间: 2022-05-30
• 期刊: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Histoplasma Seropositivity in TB Patients in The Gambia: Evidence to Drive Research on a High-Priority Fungal Pathogen.

• DOI: 10.1093/ofid/ofad510
• 发表时间: 2023-10
• 期刊: OPEN FORUM INFECTIOUS DISEASES
• 影响因子: 4.2
• 作者: Cornell, Tessa R.;Jobe, Dawda;Donkor, Simon;Wootton, Daniel G.;Pinchbeck, Gina;Sutherland, Jayne S.;Scantlebury, Claire Elizabeth
• 通讯作者: Scantlebury, Claire Elizabeth

The household economic burden of drug-susceptible TB diagnosis and treatment in The Gambia.

• DOI: 10.5588/ijtld.22.0091
• 发表时间: 2022-12-01
• 期刊: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
• 作者: Devoid I;Sillah AK;Sutherland J;Owolabi O;Ivanova O;Govathson C;Hirasen K;Davies M;Lönnroth K;Loum I;Touray A;Charlambous S;Evans D;Quaife M
• 通讯作者: Quaife M