Development and evaluation of a yoga-based cardiac rehabilitation programme (Yoga-CaRe) for secondary prevention of myocardial infarction

用于心肌梗死二级预防的基于瑜伽的心脏康复计划（Yoga-CaRe）的开发和评估

• 批准号: MR/J000175/1
• 负责人: Sanjay Kinra
• 金额: $ 127.73万
• 依托单位: London School of Hygiene & Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FJ000175%2F1
• 关键词: Development; evaluation; yoga; based; cardiac

Cardiac rehabilitation (CR) programmes aim to reduce the risk of death or illness following a heart attack; in order to help the patient regain their health and ability to participate in normal day-to-day activities. CR programmes attempt to do this by improving the physical fitness of the patient, reducing stress levels and encouraging long-term lifestyle changes (such as quitting smoking, reducing alcohol consumption and eating a healthy diet). There is strong scientific evidence from developed countries, such as the UK, to show that CR programmes are effective in doing this.In developed countries, CR programmes are usually delivered as a combination of exercise and educational sessions, run by large multi-disciplinary teams including nurses, occupational therapists, doctors, psychologists, pharmacists, dieticians and counsellors. However, in developing countries such as India this is often regarded as an unaffordable luxury; as a result CR programmes are virtually non-existent.The practice of yoga, a traditional Indian mind-body discipline has similar short term objectives to a CR programme (improved physical fitness, stress reduction and lifestyle change) and a similar method of delivery (combined exercise-education sessions). However, instead of a large multi-disciplinary team only one individual is needed: the yoga teacher. A yoga-based CR programme is therefore likely to be more cost-effective to deliver on a large-scale in the Indian setting. It is also likely to be more culturally appropriate. We suggest that the development of a yoga-based CR programme will have greater acceptability both in India and also amongst particular groups in the UK (such as Asian Indian ethnic groups, women and the elderly) who currently have a low rate of uptake of traditional CR programmes.This project will combine two complementary studies: (i) a large randomised controlled trial in India to evaluate the effectiveness of a specially designed yoga-based CR programme compared to standard care; (ii) a smaller in-depth study of the underlying physiological mechanisms, carried out in the UK using high-tech exercise laboratory facilities. We will also investigate the cost effectiveness of the yoga-based CR package compared to current standard care; such information will be of great use to policymakers in scaling up the intervention if found to be effective.The large trial in India will randomise 4000 heart attack patients from 16 hospitals in India to receive either a specially designed yoga-based CR package or to receive standard care. Patients will be followed up for one year and we will compare the number of deaths, health-related quality of life and subsequent heart attacks and strokes in the two groups. In the UK patients already get CR. We will randomise 80 patients to get yoga classes in addition to their standard CR, or to just to receive standard care and carry out detailed physiological and metabolic tests, this component will allow us to understand how yoga may have beneficial effects on heart health.If found to work, the new CR programme will on implementation lead to considerable savings in lives, quality of life and economic productivity in both countries. A second outcome of this research programme will be a markedly improved scientific knowledge base on the processes underlying the health benefits of yoga, about which little is currently known.

心脏康复（CR）计划旨在降低心脏病发作后死亡或患病的风险;以帮助患者恢复健康和参与正常日常活动的能力。CR计划试图通过改善患者的身体健康，减少压力水平和鼓励长期改变生活方式（如戒烟，减少饮酒和健康饮食）来实现这一目标。来自英国等发达国家的强有力的科学证据表明，CR计划可以有效地做到这一点。在发达国家，CR计划通常是以运动和教育课程相结合的方式提供，由大型多学科团队管理，包括护士、职业治疗师、医生、心理学家、药剂师、营养师和咨询师。然而，在印度等发展中国家，这往往被视为一种负担不起的奢侈品;因此，CR计划几乎不存在。瑜伽练习，一种传统的印度身心学科，与CR计划有着类似的短期目标（改善身体健康，减轻压力和改变生活方式），以及类似的交付方法（结合锻炼和教育课程）。然而，我们不需要一个庞大的多学科团队，只需要一个人：瑜伽老师。因此，以瑜伽为基础的CR方案在印度大规模实施可能更具成本效益。它也可能在文化上更合适。我们认为，发展瑜伽为基础的CR计划将有更大的接受度，无论是在印度，也在英国的特定群体该项目将联合收割机结合两项相辅相成的研究：（i）在印度进行的一项大型随机对照试验，以评估与标准护理相比，专门设计的基于瑜伽的CR计划的有效性;（ii）在英国利用高科技运动实验室设施，对运动背后的生理机制进行规模较小的深入研究。我们还将调查与目前的标准护理相比，基于瑜伽的CR包的成本效益;如果发现有效，这些信息将对政策制定者扩大干预规模非常有用。印度的大型试验将随机选择来自印度16家医院的4000名心脏病发作患者，接受专门设计的基于瑜伽的CR包或接受标准护理。患者将被随访一年，我们将比较两组的死亡人数、健康相关的生活质量以及随后的心脏病发作和中风。在英国，患者已经获得CR。我们将随机抽取80名患者，让他们在标准CR的基础上参加瑜伽课程，或者只是接受标准护理并进行详细的生理和代谢测试，这将使我们了解瑜伽如何对心脏健康产生有益影响。如果发现有效，新的CR项目的实施将大大节省两国的生命，生活质量和经济生产力。这项研究计划的第二个成果将是一个显着改善的科学知识基础上的过程，基本的健康益处的瑜伽，这是目前所知甚少。

项目成果

Yoga Program for Type 2 Diabetes Prevention (YOGA-DP) Among High-Risk People: Qualitative Study to Explore Reasons for Non-participation in a Feasibility Randomized Controlled Trial in India.

• DOI: 10.3389/fpubh.2021.682203
• 发表时间: 2021
• 期刊: Frontiers in public health
• 影响因子: 5.2
• 作者: Mishra P;Greenfield SM;Harris T;Hamer M;Lewis SA;Singh K;Nair R;Mukherjee S;Krishnamurthy Manjunath N;Harper DR;Tandon N;Kinra S;Prabhakaran D;Chattopadhyay K
• 通讯作者: Chattopadhyay K

Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP): A Qualitative Study Exploring the Trial Team's Facilitators and Challenges in Conducting a Feasibility Trial in India.

• DOI: 10.1007/s13300-023-01450-0
• 发表时间: 2023-10
• 期刊: DIABETES THERAPY
• 影响因子: 3.8
• 作者: Mishra, Pallavi;Greenfield, Sheila Margaret;Harris, Tess;Hamer, Mark;Lewis, Sarah Anne;Singh, Kavita;Nair, Rukamani;Mukherjee, Somnath;Tandon, Nikhil;Kinra, Sanjay;Manjunath, Nandi Krishnamurthy;Prabhakaran, Dorairaj;Chattopadhyay, Kaushik
• 通讯作者: Chattopadhyay, Kaushik

PO138 Factors Associated With Heart Rate at Discharge Following Acute Myocardial Infarction: Data From Yoga-Care Trial

PO138 与急性心肌梗死后出院时心率相关的因素：来自瑜伽护理试验的数据

• DOI: 10.1016/j.gheart.2018.09.130
• 发表时间: 2018
• 期刊: Global Heart
• 影响因子: 3.7
• 作者: Chandrasekaran A

Feasibility Trial of Yoga Programme for Type 2 Diabetes Prevention (YOGA-DP) among High-Risk People in India: A Qualitative Study to Explore Participants' Trial- and Intervention-Related Barriers and Facilitators.

• DOI: 10.3390/ijerph19095514
• 发表时间: 2022-05-01
• 期刊: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
• 作者: Mishra, Pallavi;Harris, Tess;Greenfield, Sheila Margaret;Hamer, Mark;Lewis, Sarah Anne;Singh, Kavita;Nair, Rukamani;Mukherjee, Somnath;Manjunath, Nandi Krishnamurthy;Tandon, Nikhil;Kinra, Sanjay;Prabhakaran, Dorairaj;Chattopadhyay, Kaushik
• 通讯作者: Chattopadhyay, Kaushik

Development process of a yoga-based cardiac rehabilitation programme (Yoga-CaRe)

基于瑜伽的心脏康复计划（Yoga-CaRe）的开发过程

• 发表时间: 2013
• 作者: Chattopadhyay K