PERITONEAL DIALYSIS ADEQUACY IN CHILDREN

儿童腹膜透析患者可能患有生长发育障碍 发育迟缓、营养不良和神经认知发育受损。 解决这些个别问题的努力受到以下限制 透析提供不一致和缺乏适合年龄的 透析充分性的定义。提出了一种随机的、前瞻性的、 常规腹膜透析与强化腹膜透析的交叉比较， 增强型小分子清除剂对神经细胞的影响 认知功能、瘦体重增长和膳食蛋白质摄入量。

Pediatric peritoneal dialysis patients may suffer from growth retardation, malnutrition and impaired neurocognitive development. Attempts to address these individual problems have been limited by inconsistent dialysis delivery and the lack of an age-appropriate definition of dialysis adequacy. Proposed is a randomized, prospective, cross-over comparison of usual and intensive peritoneal dialysis, assessing the effect of enhanced small molecule clearance on neuro- cognitive function, growth of lean body mass and dietary protein intake.