CORE--ANIMALS

动物中心的目的是确保高质量的实验 准备.所有与动物获取、护理有关的项目， 处置将归入本核心。经验丰富的动物 技术专家将监督本建议书的所有方面， 动物： * 常规护理/喂养和繁殖 * 麻醉的选择和管理 * 手术 * MRI造影剂注射 * 实验期间动物的生理监测 * 实验后生理监测，确保健康恢复 * 与MRI探头制造商合作 该核心的服务将使调查人员能够自由地进行 他们的实验，同时确保动物得到照顾， 符合加州理工学院和NIH指南的人道方式。

The purpose of the Animal Core is to insure a high quality experimental preparation. All items pertaining to animal acquisition, care, and disposal will be subsumed under this Core. An experienced Animal Technologist will oversee all aspects of this Proposal that involve animals: * Routine care/feeding and breeding * Choice and administration of anesthesia * Surgery * Injection of MRI contrast agents * Physiological monitoring of animal during experiments * Physiological monitoring post-experiment to ensure healthy recovery * Collaborate with MRI probe builders The services of this Core will leave the investigators free to conduct their experiments, while ensuring that the animals are cared for in a humane manner consistent with Caltech and NIH guidelines.