CORE--ANIMALS

动物核心的目的是确保高质量的实验 准备工作。所有与动物获取、护理和管理有关的物品 处置将归入本核心。一只经验丰富的动物 技术专家将监督该提案的所有方面，包括 动物： *常规护理/喂养和繁殖 *麻醉的选择和给药 *外科手术 *注射磁共振造影剂 *在实验期间对动物进行生理监测 *实验后生理监测，确保健康恢复 *与磁共振探头构建商协作 这一核心的服务将使调查人员能够自由地进行 他们的实验，同时确保动物在一个 符合加州理工学院和美国国立卫生研究院指导方针的人性化方式。

The purpose of the Animal Core is to insure a high quality experimental preparation. All items pertaining to animal acquisition, care, and disposal will be subsumed under this Core. An experienced Animal Technologist will oversee all aspects of this Proposal that involve animals: * Routine care/feeding and breeding * Choice and administration of anesthesia * Surgery * Injection of MRI contrast agents * Physiological monitoring of animal during experiments * Physiological monitoring post-experiment to ensure healthy recovery * Collaborate with MRI probe builders The services of this Core will leave the investigators free to conduct their experiments, while ensuring that the animals are cared for in a humane manner consistent with Caltech and NIH guidelines.