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FLUCONAZOLE KINETICS AND FLUCONAZOLE-FK506 INTERACTION IN TRANSPLANT PATIENTS

FLUCONAZOLE KINETICS AND FLUCONAZOLE-FK506 INTERACTION IN TRANSPLANT PATIENTS
移植患者中氟康唑动力学和氟康唑-FK506 相互作用
批准号：
5218380
负责人：
Raman Venkataramanan
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5218380
关键词：
FK506 antifungal agents clinical research drug interactions drug screening /evaluation fluconazole human subject human therapy evaluation liver transplantation oral administration pharmacokinetics

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英文摘要
Antifungal therapy is commonly required in patients on immunosuppressive therapy. However, coadministration of the two therapies has potential for drug interactions. This study will characterize the kinetics of fluconazole after oral administration in liver transplant patients. It will also characterize the interaction between fluconazole and Tacrolismus in liver transplant patients.
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