DRUG EXCRETION IN TRANSPLANT PATIENTS
DRUG EXCRETION IN TRANSPLANT PATIENTS
批准号:
6114600
负责人:
Raman Venkataramanan
金额:
$2.9万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-12-01 至 2003-11-30
关键词:
biomarker blood chemistry cephalosporins clinical research clinical trials drug metabolism glomerular filtration halobenzene human subject ion transport kidney disorder diagnosis kidney function kidney pharmacology kidney transplantation p aminohippurate postoperative state renal tubular transport urinalysis
中文摘要
本研究的目的是评估肾移植患者的肾功能。
病人。肾功能是通过给予肾脏标记物来确定的--
PAH、异硫氰酸酯和头孢氨苄对肾移植患者的积极研究
肾小管阴离子分泌、滤过和活动性肾小管分泌。12
肾移植患者将分成2组,6名将接受
异硫氰酸酯和PAH在3小时内,其他6人将收到
头孢氨苄作为一种丸剂,研究超过8小时。药品将被检测在
采集血浆和尿液,并将结果与6名正常人进行比较
物联网/多环芳烃。
英文摘要
Purpose of the study is to assess renal function in renal transplant
patients. Kidney function is determined by administering renal markers--
PAH, Iothalamate and Cephalexin to renal transplant pts to study active
tubular anionic secretion, filtration, and active tubular secretion. 12
kidney transplant pts will be divided into 2 groups, 6 will receive
Iothalamate and PAH over a 3 hr period, the other 6 will receive
Cephalexin as a bolus and studied over 8 hrs. Drugs will be assayed in
plasma and urine collected, and results compared w/6 normals receiving
Ioth/PAH.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
EFFECT OF MILK THISTLE ON THE PHARMACOKINETICS OF MIDAZOLAM
-
批准号:7201092
-
项目类别:
-
资助金额:$2.53万
-
财政年份:2005
-
负责人:Raman Venkataramanan
-
依托单位:
EFFECT OF VALERIAN ON PHARMACOKINETICS OF ACETAMINOPHEN
-
批准号:7201119
-
项目类别:
-
资助金额:$1.43万
-
财政年份:2005
-
负责人:Raman Venkataramanan
-
依托单位:
MDR1 Gene Polymorphism and Pharmacokinetics of Ritonavir
-
批准号:6974721
-
项目类别:
-
资助金额:$0.66万
-
财政年份:2004
-
负责人:Raman Venkataramanan
-
依托单位:
DRUG EXCRETION IN TRANSPLANT PATIENTS
-
批准号:6304690
-
项目类别:
-
资助金额:$0.3万
-
财政年份:1999
-
负责人:Raman Venkataramanan
-
依托单位:
DRUG EXCRETION IN TRANSPLANT PATIENTS
-
批准号:6219259
-
项目类别:
-
资助金额:$0.3万
-
财政年份:1998
-
负责人:Raman Venkataramanan
-
依托单位:
DRUG EXCRETION IN TRANSPLANT PATIENTS
-
批准号:6275835
-
项目类别:
-
资助金额:$1.91万
-
财政年份:1997
-
负责人:Raman Venkataramanan
-
依托单位:
Feasibility and Safety of Vaginal Administration of 17-hydroxyprogesterone caproate
-
批准号:8984568
-
项目类别:
-
资助金额:$1.41万
-
财政年份:--
-
负责人:Raman Venkataramanan
-
依托单位:
FLUCONAZOLE KINETICS AND FLUCONAZOLE-FK506 INTERACTION IN TRANSPLANT PATIENTS
-
批准号:5218380
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:Raman Venkataramanan
-
依托单位:--
Basic/Translational Investigations on Buprenorphine
-
批准号:9119109
-
项目类别:
-
资助金额:$22.83万
-
财政年份:--
-
负责人:Raman Venkataramanan
-
依托单位:
海外基金