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BIOAVAILIBILITY AND PHYSIOLOGIC EFFECTS OF ADRENAL ANDROGEN REPLACEMENT

BIOAVAILIBILITY AND PHYSIOLOGIC EFFECTS OF ADRENAL ANDROGEN REPLACEMENT
肾上腺雄激素替代的生物利用度和生理效应
批准号：
5220148
负责人：
PETER R CASSON
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5220148
关键词：
aging clinical research clinical trials dehydroepiandrosterone dosage forms drug administration routes drug screening /evaluation endocrine pharmacology estrogens female hormone regulation /control mechanism hormone therapy human subject human therapy evaluation pharmacokinetics postmenopause

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中文摘要
翻译
研究脱氢表雄酮的替代潜力。我们想捐出10 绝经后妇女脱氢表雄酮微粉化随机安慰剂对照研究 时尚和10名绝经后妇女阴道微粉化脱氢表雄酮。它是 预计DHEA更换将带来多项好处 效果，补充雌激素，并可能有效地延缓 衰老中的一些方面。这将允许减少 雌激素在更年期更年期替代疗法中的作用 是可以预料到的。
英文摘要
Investigate the potential of DHEA replacement. We wish to give 10 postmenopausal women micronized DHEA in a randomized placebo controlled fashion and 10 postmenopause women vaginal micronized DHEA. It is expected that DHEA replacement will result in multiple beneficial effects, complimentary to estrogen, and may be effective in retarding some aspects in aging. This would allow for reduction of the dose of estrogen in menopausal replacement regimen to the point where amenorrhea can be expected.
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会议论文
Metformin Use During in Vitro Fertilization in Polycystic Ovary Syndrome
Metformin Use During in Vitro Fertilization in Polycystic Ovary Syndrome
THE EFFECT OF OOPHORECTOMY IN POSTMENOPAUSAL WOMEN
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