UKDP: Integrated DEmentiA research environment (IDEA)

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The UK Dementias Platform (UKDP) is a radically new approach to dementias research. It brings together data fromaround 2,000,000 study participants from 22 cohorts to try and discover the causes of dementia and to find out ways ofslowing it down. The platform has been funded to the level of £12M.In this proposal we want to improve UK infrastructure for dementia research so that the most can be made of theopportunity provided by UKDP. We wan to improve the infrastructure by buying important pieces of equipment that will putthe UK at the forefront of dementia research worldwide and by establishing networks of scientists who will work together tomake best use of the equipment.The three themes of the proposal are imaging, informatics and stem cells.For imaging we want to establish a network of PET/MR scanning facilities across the UK so that the molecular processesgoing on inside the brain that cause dementia can be studied.For informatics we want to be bring together bas many different types of data as possible and make it easy as possible forscientists to use themFor stem cells we want to take cells form adults with and without dementia to find out how cells change as the dementiasprocess begins and progresses.We believe these proposals will raise standards, reduce costs, and deliver innovative and coordinated research, makingthe UK an internationally unique place to study dementia.