MULTIMEDIA SICKNESS SIMULATOR FOR PREADOLESCENTS

青春期前多媒体疾病模拟器

• 批准号: 2869555
• 负责人: Michael Anderson
• 金额: $ 10万
• 依托单位: HEALTH MEDIA LAB, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-10 至 2000-02-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2869555
• 关键词: clinical research; computer assisted instruction; computer human interaction; computer program /software; computer simulation; computer system design /evaluation; disease /disorder prevention /control; education evaluation /planning; health behavior; health education; human subject; interactive multimedia; middle childhood (6-11); pathologic process; virus diseases

In Phase I we will develop prototype 3D simulation software that will allow users to manipulate a viral infection and to observe consequences, complexity, and effects over time. Phase I subjects will see the symptoms of a cold, and trace a cold's gradual one- or two-day onset. We will illustrate how airborne cold viruses are inhaled or spread by hand to mouth, eyes, or nose; how viruses attach to and enter host cells; how they break down and make copies in host cells; how they destroy host cells, and invade other cells. As the cold progresses, they will be able to watch antibodies latch onto viruses, macrophages digest the combined viruses and antibodies, see nasal mucus thicken, and the body recover. Subjects will also learn why schools and crowded areas are likely places to catch colds, and the importance of hand washing in preventing colds. At three points during the prototype development we will collect data from 8 to 1l year old target group subjects. Data will include 1) qualitative, focus group data on user preferences; and 2) quantitative, questionnaire data on knowledge of colds, and intended hand washing behavior. Results of Phase I focus group discussions and questionnaires will be reported, and used in designing Phase II. PROPOSED COMMERCIAL APPLICATIONS: We are in a second level of negotiations with The Learning Co.. (TLC)(www.softkey.com) to distribute our software, including this product. TLC develops, publishes and markets software for every age. Its products are sold in N. America to schools, online, direct marketing & OEM (original equipment manufacturer); subsidiaries in Europe, Japan, & Australia; Latin America, and the Pacific Rim. Well known TLC products include Reader Rabbit, Mavis Beacon, Sesame Street, PrintMaster, Oregon Trail. TLC recently merged with Broderbund.

在第一阶段，我们将开发原型3D模拟软件，使用户能够操纵病毒感染，并观察随着时间的推移的后果，复杂性和影响。第一阶段的受试者将看到感冒的症状，并跟踪感冒的逐渐一两天发作。我们将说明空气中的感冒病毒如何被吸入或通过手传播到嘴、眼睛或鼻子;病毒如何附着并进入宿主细胞;它们如何在宿主细胞中分解和复制;它们如何破坏宿主细胞并入侵其他细胞。随着感冒的进展，他们将能够看到抗体与病毒结合，巨噬细胞消化结合的病毒和抗体，看到鼻粘液分泌，身体恢复。受试者还将学习为什么学校和拥挤的地方很可能感冒，以及洗手在预防感冒方面的重要性。在原型开发过程中的三个时间点，我们将收集8至11岁目标组受试者的数据。数据将包括1）关于用户偏好的定性焦点组数据;以及2）关于感冒知识和预期洗手行为的定量问卷调查数据。将报告第一阶段重点小组讨论和问卷调查的结果，并用于设计第二阶段。建议的商业应用：我们正在与学习公司进行第二层次的谈判。（TLC）（www.softkey.com）分发我们的软件，包括本产品。TLC为每个年龄段开发、出版和销售软件。其产品在N.美国的学校，在线，直接营销和OEM（原始设备制造商）;在欧洲，日本和澳大利亚的子公司;拉丁美洲和太平洋沿岸。著名的TLC产品包括Reader Rabbit，Mavis Beacon，Sesame Street，PrintMaster，俄勒冈州Trail。TLC最近与Broderbund合并。