AREA BEAM EQUALIZATION FOR X-RAY ANGIOGRAPHY

X 射线血管造影的区域束均衡

• 批准号: 6030785
• 负责人: SABEE MOLLOI
• 金额: $ 21.7万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-15 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6030785
• 关键词: X ray; angiography; bioimaging /biomedical imaging; biomedical equipment development; computer assisted diagnosis; digital imaging; image enhancement; phantom model; swine

DESCRIPTION (Adapted from Applicant's Abstract): The applicants proposed to develop an x-ray beam equalization technique for digital fluoroscopic applications that will produce an equalized radiograph with minimal image artifacts and tube loading. More specifically the aim are: (1) Investigation of the effect of piston size and the extent of focal spot blurring on image equalization using physical phantoms. (2) design and construction of the necessary hardware and software for an automated image equalization system. (3) Investigation of the hypothesis that x-ray beam equalization produces an image with significantly improved signal-to-noise ratio (S/N) and minimal image artifacts using physical phantoms. (4) Investigation of the hypothesis that x-ray beam equalization produces significantly improved iodine quantification using physical phantoms. (5) Investigation of the hypothesis that the x-ray beam equalization technique can be reliably utilized during coronary angiography using a swine animal model. The results of this research will provide fundamentally improved images for both low and high frame rate applications. This technique has several potential applications. One of the applications is the elimination of bright spots and improvement of image S/N in digital angiographic images. This is particularly true for cardiac imaging where the heart is very dense near a very transmissive lung field which causes a significant S/N degradation over the heart region. The elimination of bright spots by x-ray beam equalization allows the entire image to be acquired with optimal S/N. Furthermore, this technique provides significantly improved iodine quantification in the under penetrated regions of the image.

描述(改编自申请人摘要)：申请人建议 开发一种用于数字透视的X射线束均衡技术 将生成具有最小图像的均衡X光照片的应用程序 艺术品和管子装载。更具体地说，目标是：(1) 活塞尺寸和焦斑范围的影响研究 使用物理幻影对图像均衡进行模糊处理。(2)设计及 构建自动化映像所需的硬件和软件 均衡化系统。(3)对x射线束假设的探讨 均衡产生的图像具有显著改善的信噪比 比率(S/N)和使用物理模型的最小图像伪影。(4) 关于X射线束均衡化产生的假设的探讨 使用物理模体显著改进了碘的量化。(5) 关于X射线束均衡技术假设的探讨 在猪的冠状动脉造影术中可以可靠地使用 模特。这项研究的结果将从根本上改进 适用于低帧频和高帧频应用的图像。这项技术具有 几种潜在的应用。其中一个应用是消除 数字血管造影图像中亮点的消除和图像S/N的改善。 对于心脏密度非常高的心脏成像来说尤其如此 靠近一个非常透射性的肺野，这会导致显著的S/N 心脏区域的退化。用x射线消除亮点 波束均衡允许以最优的S/N来获取整个图像。 此外，这项技术提供了显著改善的碘 在图像的未穿透区域中进行量化。

项目成果

X-ray beam equalization: feasibility and performance of an automated prototype system in a phantom and swine.

X 射线束均衡：模型和猪中自动化原型系统的可行性和性能。

• DOI: 10.1148/radiol.2213010183
• 发表时间: 2001
• 期刊: Radiology.
• 作者: Molloi,S;VanDrie,A;Wang,F
• 通讯作者: Wang,F

Scatter and veiling glare estimation based on sampled primary intensity.

• DOI: 10.1118/1.598744
• 发表时间: 1999-11
• 期刊: Medical physics
• 影响因子: 3.8
• 作者: Y. Zhou;T. Mathur;S. Molloi

Area beam equalization: optimization and performance of an automated prototype system for chest radiography.

区域光束均衡：胸部放射线摄影自动化原型系统的优化和性能。

• DOI: 10.1016/s1076-6332(03)00730-x
• 发表时间: 2004
• 期刊: Academic radiology
• 影响因子: 4.8
• 作者: Xu,Tong;Shikhaliev,PoladM;Berenji,GholamR;Tehranzadeh,Jamshid;Saremi,Farhood;Molloi,Sabee
• 通讯作者: Molloi,Sabee

Patient-specific region-of-interest fluoroscopy device for X-ray dose reduction.

用于减少 X 射线剂量的患者特定感兴趣区域透视装置。

• DOI: 10.1148/radiol.2262011812
• 发表时间: 2003
• 期刊: Radiology.
• 作者: Xu,Tong;Le,HuyQuang;Molloi,Sabee
• 通讯作者: Molloi,Sabee