QUALITY OF WELL-BEING (QWB) SCALE REVISION PROJECT

描述：拟议项目的具体目标是：开发和开发 验证QWB的自我管理表格，称为QWB-SA； 进行偏好测量研究，以获得评分系统 为QWB-SA；并开发一个针对视觉的评分系统 QWB-SA。 目的1：编制和验证QWB-SA。目标1涉及几个步骤。第一 调查人员将对QWB中目前的症状清单进行扩展。一个 QWB-SA的草稿(已经制定)将发送给15名专家进行 查看和评论。接下来，将对HRQL文献进行内容分析 执行以确定QWB-SA充分捕获的程度 现有措施中包括的项目。在对QWB进行进一步修订后， 完成后，QWB-SA将在加州大学圣迭戈分校多用途关节炎中心进行试点测试 中心，以及家庭医学诊所的病人。下一步，措施 将在加州大学圣迭戈分校正在进行的研究和临床研究中进行现场测试 中锋。此外，10%(200)的分层随机抽样将 被选中进行进一步研究。这200名患者将完成 面试官对QWB和SF-36进行了适当的测试 两个时间点的制衡和管理，大约一个月 分离。 用于评估所开发信息的准确性的定性分析 将对200名患者的数据进行调查，使用 内部一致性分析方法。对全文的其他分析 2 000个和200个子集将包括：评估失踪情况的项目分析 所有项目的数据速率和频率分布.平均值的比较 QWB和QWB-SA得分；QWB所有成分的相关分析， QWB-SA和SF-36，以确定哪些QWB与 SF-36；以及按人口统计变量对QWB-SA进行的分分析，包括 年龄、性别和教育程度。将执行QWB的个人资料评分 使用因素分析，预期的分类包括：体力活动， 社交活动、自我照顾、行动能力、痛苦、情绪功能，以及 感官功能。因子分数将通过获取以下各项的总和来创建 每个维度的项目反应和因子得分系数分别为。 目标2：偏好测量研究，以获得一个评分系统 QWB-SA。加州大学圣迭戈分校初级保健诊所的500名患者 将被招募到拟议研究的这一阶段。他们将会是 按性别平均分配，所有人都将是成年人，约40%将是 非裔美国人或西班牙裔。所有参与者将对完整案例进行评分 不同健康状态的描述和组成部分，使用1-100分 比例。对偏好数据的分析将包括两个阶段： 区间标度性质的确立及其发展 判断模型；以及价值权重的估计。 目标3：疾病特异度与一般量度。在这一阶段， 研究人员建议开发一种特定于视觉的评分系统 为QWB-SA。250名接受第一眼治疗的患者 白内障摘除将被纳入这项研究。参与者必须是 年龄超过35岁的。排除标准包括：不能说话 英语；严重听力障碍；认知障碍；患者 同时接受青光眼、角膜或玻璃体视网膜手术； 外伤性白内障患者；以及视力受损的患者 严重的是他们不能填写一份自我管理的表格。除了……之外 QWB-SA数据，将收集视力数据，患者将 完成VF-14，这是一种专门为 视觉问题。另外，白内障症状评分表和简短的医疗记录 将对患者进行共病评定量表的评定。心理测量学 将使用方法来评估QWB-SA和 与视力和特定视力有关的特定视力测量 结果衡量标准。

DESCRIPTION: The specific aims of the proposed project are: to develop and validate a self-administered form of the QWB, referred to as the QWB-SA; to perform preference measurement studies in order to obtain a scoring system for the QWB-SA; and to develop a vision specific scoring system for the QWB-SA. Aim 1: Develop and validate QWB-SA. Aim 1 involves several steps. First the investigators will expand on the current list of symptoms in the QWB. A draft of the QWB-SA (already developed) will be sent to 15 experts for review and comment. Next, a content analysis of the HRQL literature will be performed to determine the degree to which the QWB-SA adequately captures items included in existing measures. After further revisions of the QWB are complete, the QWB-SA will be pilot tested at the UCSD Multipurpose Arthritis Center, and with patients in Family Medicine Clinics. Next, the measure will be field tested in ongoing studies at UCSD and in clinical research centers. In addition, a stratified random sample of 10 percent (200) will be selected for further study. These 200 patients will complete the interviewer administered QWB and the SF-36, with appropriate counterbalancing and administration at two time points with about one-month separation. A qualitative analysis for assessing the accuracy of information developed in the surveys will be performed on the 200 patients' data, using the Internal Consistency Analysis method. Additional analyses of the full 2,000, and the subset of 200, will include: item analysis to assess missing data rates and frequency distributions for all items; comparisons of mean QWB and QWB-SA scores; correlation analyses of all components of the QWB, QWB-SA and SF-36 to determine which of the QWB's is most correlated with the SF-36; and subanalyses of the QWB-SA by demographic variables, including age, gender, and education. Profile scoring of the QWB will be performed using factor analyses, with expected clusters including: physical activity, social activity, self-care, mobility, pain, emotional functioning, and sensory functioning. Factor scores will be created by obtaining the sum of item responses and factor score coefficients separately for each dimension. Aim 2: Preference measurement study to obtain a scoring system for the QWB-SA. Five hundred patients from the primary care clinics at the UCSD will be recruited into this phase of the proposed research. They will be evenly divided by gender, all will be adults, and about 40 percent will be African American or Hispanic. All participants will rate complete case descriptions and components of different health states, using a 1-100 point scale. Analyses of the preference data will involve two phases: establishment of the interval scale property and the development of the model of judgment; and, estimation of value weights. Aim 3: Disease-specific versus general measure. In this phase of the study, the investigators propose to develop a vision specific scoring system for the QWB-SA. Two hundred fifty patients undergoing their first eye cataract extraction will be recruited into the study. Participants must be older than 35 years of age. Exclusion criteria include: inability to speak English; serious hearing impairment; cognitive impairment; patients undergoing simultaneous glaucoma, corneal or vitro-retinal procedures; patients with traumatic cataracts; and patients with visual impairment so severe that they cannot complete a self-administered form. In addition to the QWB-SA data, data will be collected on visual acuity and patients will complete the VF-14, a functional status measure designed specifically for visual problems. Also, a cataract symptom score scale and a brief medical co-morbidity scale will be administered to the patients. Psychometric methods will be used to evaluate items from the QWB-SA and the vision-specific measures in relation to visual acuity and a vision specific outcome measure.