Drinking-water under a "One Health" lens: quantifying microbial contamination pathways between livestock and drinking-water

“同一个健康”视角下的饮用水：量化牲畜和饮用水之间的微生物污染途径

• 批准号: MR/P024920/1
• 负责人: Jim Wright
• 金额: $ 76.88万
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FP024920%2F1
• 关键词: Drinking; water; under; Health; lens

Diarrhoeal disease and lack of access to safe water remain significant public health issues in developing countries. There is also growing concern about the potential for disease, including diarrhoeal infections, to be transmitted from livestock to humans. This project addresses the potential drinking-water contamination risks to human health in rural sub-Saharan Africa, where people and livestock often live in close proximity. Preliminary fieldwork will be carried out in rural Kenya, building on an ongoing study that is simultaneously recording human and livestock disease in ten villages. The fieldwork will test different techniques to identify contamination hazards from livestock, alongside water quality testing and recording of diarrhoea in children. These techniques will include the use of GPS collars to track cattle movements, maps of hazardous areas created by the communities themselves, and also checklists for recording signs of livestock hazards at water sources and around water stored in the home. We will look at how feasible it is to record hazards using these techniques. We will also statistically assess whether we find greater water contamination and greater diarrhoea in children where there are more recorded hazards. Since measurement of water contamination used in such areas is based on bacteria found in both livestock and humans, the project will also work on affordable ways of testing for micro-organisms that are specifically found in livestock faeces versus those found in human faeces. If successful, such techniques could be used to investigate the importance of different sources of faecal contamination of drinking-water. This in turn could help manage the safety of rural water sources like wells and rainwater and better protect drinking-water stored in the home from contamination through livestock. Because this complex problem requires a wide range of expertise, during the project we will strength our academic team to include more disciplines, particularly specialists in child health and social sciences. The tools for identifying hazards from livestock will be made widely available at the end of the project and UK expertise in the microbiological laboratory techniques will be shared with Kenyan collaborators. The experience gained will be used to build up contacts and develop a plan and team for a larger-scale study of livestock hazards, water contamination, and diarrhoeal disease risk in several countries.

腹泻病和缺乏安全用水仍然是发展中国家的重大公共卫生问题。人们还越来越担心疾病，包括肠道感染，可能从牲畜传染给人类。这一项目针对撒哈拉以南非洲农村地区饮用水污染对人类健康的潜在风险，那里的人和牲畜往往生活在很近的地方。初步的实地工作将在肯尼亚农村开展，以正在进行的一项研究为基础，该研究同时记录了10个村庄的人类和牲畜疾病。实地工作将测试不同的技术，以确定牲畜的污染危害，以及水质测试和儿童腹泻记录。这些技术将包括使用全球定位系统项圈跟踪牛群的移动，社区自己绘制危险地区地图，以及记录水源和家中储水周围牲畜危险迹象的清单。我们将研究使用这些技术记录危害的可行性。我们还将进行统计评估，以确定在记录的危害更多的地方，我们是否发现水污染更严重，儿童腹泻更严重。 由于在这些地区使用的水污染测量方法是根据牲畜和人体中发现的细菌，该项目还将研究负担得起的方法，测试牲畜粪便中特有的微生物与人类粪便中的微生物。如果成功的话，这种技术可用于调查粪便污染饮用水的不同来源的重要性。这反过来可以帮助管理农村水源的安全，如威尔斯和雨水，并更好地保护储存在家中的饮用水免受牲畜污染。 由于这个复杂的问题需要广泛的专业知识，在项目期间，我们将加强我们的学术团队，包括更多的学科，特别是在儿童健康和社会科学的专家。在项目结束时，将广泛提供用于确定牲畜危害的工具，并将与肯尼亚合作者分享英国在微生物实验室技术方面的专门知识。所取得的经验将用于建立联系，并为在几个国家进行更大规模的牲畜危害、水污染和肠道疾病风险研究制定计划和组建团队。

项目成果

A longitudinal study of the association between domestic contact with livestock and contamination of household point-of-use stored drinking water in rural Siaya County (Kenya).

• DOI: 10.1016/j.ijheh.2020.113602
• 发表时间: 2020-09
• 期刊: International journal of hygiene and environmental health
• 影响因子: 6
• 作者: Trajano Gomes da Silva D;Ebdon J;Okotto-Okotto J;Ade F;Mito O;Wanza P;Kwoba E;Mwangi T;Yu W;Wright JA
• 通讯作者: Wright JA

A mixed methods study to evaluate participatory mapping for rural water safety planning in western Kenya.

• DOI: 10.1371/journal.pone.0255286
• 发表时间: 2021
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Okotto-Okotto J;Yu W;Kwoba E;Thumbi SM;Okotto LG;Wanza P;Trajano Gomes da Silva D;Wright J
• 通讯作者: Wright J

Effect of Inter-Observer Variation on the Association between Contamination Hazards and the Microbiological Quality of Water Sources: A Longitudinal Study.

• DOI: 10.3390/ijerph17249192
• 发表时间: 2020-12-09
• 期刊: International journal of environmental research and public health
• 作者: Okotto-Okotto J;Trajano Gomes da Silva D;Kwoba E;Thumbi SM;Wanza P;Yu W;Wright JA
• 通讯作者: Wright JA

An Assessment of Inter-Observer Agreement in Water Source Classification and Sanitary Risk Observations.

• DOI: 10.1007/s12403-019-00339-3
• 发表时间: 2020
• 期刊: Exposure and health
• 影响因子: 6.7
• 作者: Okotto-Okotto J;Wanza P;Kwoba E;Yu W;Dzodzomenyo M;Thumbi SM;da Silva DG;Wright JA
• 通讯作者: Wright JA

Modelling seasonal household variation in harvested rainwater availability: a case study in Siaya County, Kenya.

• DOI: 10.1038/s41545-023-00247-9
• 发表时间: 2023
• 期刊: NPJ clean water
• 影响因子: 11.4