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MULTI-FREQUENCY ARRAY FOR HARMONIC IMAGING

用于谐波成像的多频阵列

基本信息

批准号：
6071774
负责人：
BAHRAM JADIDIAN
金额：
$ 9.95万
依托单位：
LAYERED MANUFACTURING, INC.
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
起止时间：
2000-03-01 至 2001-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6071774
关键词：
bioimaging /biomedical imaging biomedical equipment development contrast media imaging /visualization /scanning physical process sound frequency technology /technique development

项目摘要

The proposed study will develop a novel, high dynamic range multi- frequency transducer array designed for broad-band tissue imaging. The new array would utilize elements of the same or different materials resonating in different thickness modes to permit operating at the subharmonic, first harmonic and second harmonic frequencies. One element will be optimized for transmit and the other two optimized for receive. In this study, the first harmonic transmit/receive frequency will be 5.0 MHz with corresponding subharmonic and second harmonic echoes at 2.5 MHz and 10.0 MHz, respectively. In Phase I, Layered Manufacturing Inc., with the support of the Center for Ceramic Research of Rutgers University, will develop a small co-linear array of three parallel arrays at three different frequencies. The piezoceramic transducer arrays will be fabricated utilizing patented layered manufacturing techniques that are ideally suited for the frequency regime common to medical imaging (1-10 MHz). A feasibility demonstration will include the measurement of the scattered echo returns from a fluid with a microbubble- based ultrasound contrast agent. In Phase II, a 2-D array will be fabricated, interspersed with multi-frequency transducer elements, and the various imaging modes used to image animals, with and without an ultrasound contrast agent. PROPOSED COMMERCIAL APPLICATIONS: If the design of a multi-frequency transducer array proves successful, then Layered Manufacturing Inc. is prepared to license the technology to all ultrasound system companies. LMI is also prepared to commercially provide special transducer arrays for specific applications, particularly at high frequencies, above 10 MHz.

该研究将开发一种新型的、高动态范围的多频换能器阵列，用于宽带组织成像。新的阵列将利用相同或不同材料的元件，以不同的厚度模式谐振，以允许在次谐波、第一谐波和第二谐波频率下操作。一个元件将针对发送进行优化，另外两个元件将针对接收进行优化。在本研究中，一次谐波发射/接收频率为5.0 MHz，相应的次谐波和二次谐波回波分别为2.5 MHz和10.0 MHz。在第一阶段，分层制造公司，在罗格斯大学陶瓷研究中心的支持下，将开发一种由三个不同频率的三个平行阵列组成的小型共线阵列。压电陶瓷换能器阵列将利用专利分层制造技术制造，该技术非常适合医学成像常见的频率范围（1-10 MHz）。可行性论证将包括用基于微泡的超声造影剂测量从流体返回的散射回波。在第二阶段，将制造一个2-D阵列，穿插多频换能器元件，以及用于成像动物的各种成像模式，有和没有超声造影剂。建议的商业应用：如果多频换能器阵列的设计证明是成功的，那么分层制造公司。准备将这项技术授权给所有超声系统公司。LMI还准备在商业上为特定应用提供特殊的换能器阵列，特别是在10 MHz以上的高频下。