Development of a blood-based screening test for colorectal neoplasia; biomarker expression in circulating tumor cells and tumor-derived microvesicles

开发基于血液的结直肠肿瘤筛查试验；

• 批准号: nhmrc : 1017083
• 负责人: A/Pr Michael Michael
• 金额: $ 34.27万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-blood-based-derived-microvesicles/109826
• 关键词: Development; blood; based; screening; test

A blood-based test for bowel cancer and the premalignant lesion (i.e. adenomas) has potential to improve several aspects of screening for bowel cancer – improved capacity to detect lesions in well people who do not suspect their presence, avoidance of faecal sampling and fewer false-positive results. There is no reliable simple screening test for adenomas. This study aims at developing a practical blood test based on a device that filters and enriches cells from blood that carry these markers

对肠癌和癌前病变(即腺瘤)进行血液检测有可能改进肠癌筛查的几个方面--提高在没有怀疑自己存在的健康人中检测病变的能力，避免粪便采样和减少假阳性结果。目前还没有可靠的简单的腺瘤筛查试验。这项研究旨在开发一种实用的血液测试，该设备可以过滤和丰富携带这些标志物的血液细胞