CLINICAL TRIALS OF COPING EFFECTIVENESS TRAINING IN HIV INFECTED MEN

据估计，美国有100万艾滋病毒感染者面临着慢性 和衰弱的疾病，会造成严重的心理痛苦。 医学指南没有解决艾滋病毒和艾滋病的这些负面后果 不太可能这样做，直到有来自对照临床的证据 心理社会干预在帮助艾滋病毒方面有效的试验- 感染者在发病过程中应对压力。 疾病。为了满足这一需求，我们建议进行一项随机临床试验 应对有效性培训(CET)，一种创新的艾滋病毒干预措施- 基于压力和应对措施的最新进展的感染者 理论。 我们会的； 。评估CET对HIV感染者能力的影响 减少心理困扰，增加心理幸福感。 。比较两种不同的CET维护计划的效果 维持治疗效果12个月以上。 确定痛苦和幸福感的改善程度 与坚持医疗护理的变化有关。 。找出大学英语四级考试潜在的心理和社会机制 影响心理和坚持的结果。 。通过评估CET对健康的影响来检验CET的成本效益 医疗服务利用率和医疗保健成本。 我们将随机将300名感染艾滋病毒的痛苦男性分配到三组中的一组 条件；(1)具有增强维护计划的CET(CET-E)，(2)CET 具有标准维护(CET-S)，以及(3)等待名单控制。大学英语四级考试 小组将在为期3个月的干预阶段接受培训，并 中介变量和结果变量的变化将与 对照组。在这个初始阶段之后，控制组将收到 培训和CET小组将进入维护阶段。这个 CET-S小组将每月和每两个月举行一次会议，标准系列为 助推器会议。紧接干预阶段之后，在6-和 12个月的随访，我们将评估CET和两者的效果 心理困扰和幸福感、坚持性的维持策略 去关心，去付出代价。

The estimated 1 million people in the U.S. infected with HIV face a chronic and debilitating disease that can create profound psychological distress. Medical guidelines do not address these negative consequences of hIV and are unlikely to do so until there is evidence from controlled clinical trials that psychosocial interventions are effective in helping hIV- infected persons cope with stress over the course of t heir progressive disease. To address this need, we propose a randomized clinical trial of Coping Effectiveness Training (CET), an innovative intervention for HIV- infected persons that is based on recent advances in stress and coping theory. We will; . Evaluate the effect of CET on the ability of HIV-infected men to decrease psychological distress and increase psychological well-being. . Compare the efficacy of two alternative CET maintenance programs to sustain treatment effects over 12 months. Determine the extent to which improvements in distress and well-being are associated with changes in adherence to medical care. . Identify the potential psychological and social mechanisms by which CET affects psychological and adherence outcomes. . Examine the cost effectiveness of CET by evaluating its effect on health care utilization and health care costs. We will randomly assign 300 HIV-infected, distressed men to one of three conditions; (1) CET with an enhanced maintenance program (CET-E), (2) CET with standard maintenance (CET-S), and (3) a waiting list control. The CET groups will receive training during a 3-month Intervention phase and changes in mediating and outcome variables will be compared with the control group. After this initial phase, the control group will receive training and the CET groups will proceed to the maintenance phase. The CET-S group will meet monthly and bimonthly, in a standard series of booster sessions. Immediately after the Intervention Phase and at 6- and 12-month follow-up, we will assess the effect of CET and the two maintenance strategies on psychological distress and well-being, adherence to care, and costs.