CLINICAL TRIAL OF COPING EFFECTIVENESS TRAINING

描述：拟议的研究是一项随机临床试验。 旨在帮助艾滋病毒感染者的应对有效性培训(CET)计划 人们在进展性疾病的过程中应对压力。这个 该计划是基于压力和应对理论的最新进展。这个 这项研究旨在解决五个具体目标。1.评估效果 CET对HIV感染者心理下降能力的影响 痛苦和增加心理健康。2.比较疗效 两种可供选择的CET维持计划以维持治疗效果 超过12个月。3.确定以下方面的改进程度 痛苦和幸福与改变对 医疗护理。4.确定潜在的心理和社会问题 CET影响心理和坚持结果的机制。 5.通过评估CET在以下方面的影响来检查CET的成本效益 卫生保健利用率和卫生保健成本。评价性设计 包括在一项试验中比较CET的效果，在这项试验中，300名艾滋病毒- 被感染的男性被随机分配到三组中的一组，CET+ 增强维护(CET-E)、CET加标准维护(CET-S)，以及 最低限度的接触控制。(MCC)。紧接在3个月后 干预阶段，在6个月和12个月的随访中，CET的效果 这两个维护策略将使用以下措施进行评估 心理痛苦和幸福，坚持医疗护理，以及 成本。

DESCRIPTION: The proposed study is a randomized clinical trial of a coping effectiveness training (CET) program designed to help HIV-infected persons cope with stress over the course of the progressive disease. The program is based on recent advances in stress and coping theory. The study is designed to address five specific aims. 1. evaluate the effect of CET on the ability of HIV-infected men to decrease psychological distress and increase psychological well-being. 2. Compare the efficacy of two alternative CET maintenance programs to sustain treatment effects over 12 months. 3. Determine the extent to which improvements in distress and well-being are associated with changes in adherence to medical care. 4. Identify the potential psychological and social mechanisms by which CET affects psychological and adherence outcomes. 5. Examine the cost effectiveness of CET by evaluating its effects on health care utilization and health care costs. The evaluation design involves comparing the effects of CET in a trial in which 300 HIV- infected men are randomly assigned to one of three groups, CET plus enhanced maintenance (CET-E), CET plus standard maintenance (CET-S), and a minimal contact control. (MCC). Immediately after the 3-month intervention phase, and at 6 and 12-month follow-up, the effects of CET and the two maintenance strategies will be assessed using measures of psychological distress and well-being, adherence to medical care, and costs.