HISTOLOGICAL FINDINGS IN PREMENOPAUSAL WOMEN WITH BREAST CANCER

绝经前女性乳腺癌的组织学发现

• 批准号: 6123729
• 负责人: M MERINO
• 金额: --
• 依托单位: DIVISION OF CLINICAL SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6123729
• 关键词: aging; biopsy; breast neoplasms; clinical research; female; genetic markers; histopathology; human genetic material tag; human tissue; immunocytochemistry; in situ hybridization; oncogenes; preneoplastic state; prognosis; tumor suppressor genes

"Histological evaluation of biopsies in premenopausal patients with beast cancer will be done: 1) in search of precancerous lesions; 2) to determine type and extension of tumor and 3) to evaluate histologic factors that may predict outcome, and 4) to compare histologic changes with those of elderly females. Prognostic markers, such as cerb-2, p53 and nm23 will be studied by immunohistochemistry and in situ hybridization in order to determine their role in prognosis and to compare them with breast cancer in the elderly population."

“组织学评价活检在 绝经前乳腺癌患者将做：1）在搜索 癌前病变; 2）确定类型和扩展 肿瘤和3）评估可能预测的组织学因素 结果，和4）比较组织学变化与那些 老年女性cerb-2、p53和nm 23等预后标志物 将通过免疫组织化学和原位杂交进行研究， 以确定它们在预后中的作用，并比较它们 老年人患乳腺癌的几率"