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ISARIC Clinical Characterisation Protocol UK (CCP-UK) - a companion study for patients with Cancer and COVID-19 (CCP-CANCER-UK)

ISARIC Clinical Characterisation Protocol UK (CCP-UK) - a companion study for patients with Cancer and COVID-19 (CCP-CANCER-UK)
ISARIC 临床特征协议英国 (CCP-UK) - 针对癌症和 COVID-19 患者的伴随研究 (CCP-CANCER-UK)
批准号:
MR/V028979/1
负责人:
Carlo Palmieri
金额:
$43.95万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2020
资助国家:
英国
项目状态:
已结题
起止时间:
2020 至 --

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中文摘要
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英文摘要
2019 a new virus called SARS-CoV-2 emerged, which causes a disease termed COVID-19. This is often mild but can also be severe, leading to viral pneumonia; about one in 100 infected people are expected to die of i t. However, cancer patients are likely to be at higher risk of infection and death as they have a weakened immune system as a result of either their treatment or their cancer. We will tackle many urgent questions that need answering in cancer patients to help ensure early diagnosis, that the correct shielding advice i s given, and to enable doctors and patients to make informed decisions regarding treatment during the pandemic. This will be achieved by collecting detailed data from the over 5,000 cancer patients recruited into the main UK study which has described COVID-19 (CCP-UK study). The cancer data when linked with the rich COVID-19 data will enable the following important questions to be answered:What proportion of cancer patients die from COVID-19? How does this vary based on cancer type and cancer treatment?What are the symptoms cancer patients develop with COVID-19? Does this vary based on type of cancer and treatment?What type of cancer treatments puts people at higher risk of severe illness and death?What kind of healthcare resources are needed (including intensive care) to treat COVID-19 in cancer patients?How do the outcome of patients with cancer compare with non-cancer patients taking into account age and other illnesses?
期刊论文(3)
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会议论文
DOI: 10.3389/fimmu.2023.1146702
发表时间: 2023
期刊: Frontiers in immunology
影响因子: 7.3
作者: []
通讯作者:
DOI: 10.1001/jamanetworkopen.2022.10880
发表时间: 2022-05-02
期刊: JAMA network open
影响因子: 13.8
作者: []
通讯作者:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data