RETINAL THICKNESS ANALYSIS OF CYCLIC VISUAL ACUITY CHANGES IN MACULAR EDEMA

黄斑水肿周期性视力变化的视网膜厚度分析

• 批准号: 6297545
• 负责人: DANIEL FINKELSTEIN
• 金额: $ 0.23万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6297545
• 关键词: bioperiodicity; clinical research; edema; human subject; retina disorder; vision tests; visual perception

Two patients have been recruited and admitted to the General Clinical Research Center. These patients were admitted to study their macular edema which is a common cause of visual loss associated with several ocular conditions including diabetic retinopathy and vascular occlusions. Patients with macular edema often state that vision is worse in the morning and improves throughout the course of the day. In a previous study using the General Clinical Research Center some years ago, we found the visual acuity of 3 patients with macular edema to improve over the course of a day. This was not associated with changes in refractive error and we concluded that the fluctuation in visual acuity may well have been the result of a cyclic change in the macular edema. Since the time of that original study about 1 0 years ago, instrumentation has become available that can noninvasively measure retinal thickness as an objective measure to quantitate retinal thickness and document change in macular edema. The procedure is risk free to the patient.

两名患者已被招募并进入普通临床