RETINAL THICKNESS ANALYSIS OF CYCLIC VISUAL ACUITY CHANGES IN MACULAR EDEMA

黄斑水肿周期性视力变化的视网膜厚度分析

• 批准号: 6114363
• 负责人: DANIEL FINKELSTEIN
• 金额: $ 2.06万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114363
• 关键词: bioperiodicity; clinical research; edema; human subject; retina disorder; vision tests; visual perception

Two patients have been recruited and admitted to the General Clinical Research Center. These patients were admitted to study their macular edema which is a common cause of visual loss associated with several ocular conditions including diabetic retinopathy and vascular occlusions. Patients with macular edema often state that vision is worse in the morning and improves throughout the course of the day. In a previous study using the General Clinical Research Center some years ago, we found the visual acuity of 3 patients with macular edema to improve over the course of a day. This was not associated with changes in refractive error and we concluded that the fluctuation in visual acuity may well have been the result of a cyclic change in the macular edema. Since the time of that original study about 1 0 years ago, instrumentation has become available that can noninvasively measure retinal thickness as an objective measure to quantitate retinal thickness and document change in macular edema. The procedure is risk free to the patient.

已经招募了两名患者并住进了全科诊所 研究中心。这些患者入院检查他们的黄斑病变。 浮肿是导致视力丧失的常见原因，与几个 眼部疾病，包括糖尿病视网膜病变和血管 闭塞。黄斑水肿的患者经常说视力是 早上更糟，全天都在好转。在……里面 几年前在综合临床研究中心进行的一项研究 前，我们发现了3例黄斑水肿患者的视力 在一天的过程中不断进步。这与更改无关 在屈光不正中，我们得出结论，视力的波动 视力很可能是黄斑周期性变化的结果。 浮肿。 从大约10年前最初的研究开始， 已经有了可以非侵入性测量的仪器 视网膜厚度作为视网膜定量的客观指标 黄斑水肿的厚度和文件改变。这个过程是有风险的 对病人免费。