EXCHANGE SCIENTIST IN MASS SPECTROMETRY

涉江博士在麻省理工学院进行为期六个月的学习 光谱分析资源从1998年5月开始。他的研究重点是 用质谱学技术研究DNA与药物的相互作用 修饰过的生物分子。具体地说，有两类药物处于 研究：1)通过DNA沟槽结合的那些；2)那些 它们通过DNA嵌入结合在一起。质谱学将被用于 阐明受体-配体结合亲和力、配体结合部位 和配体结合选择性。

Dr. Shibue is on a six month study period at the Mass Spectrometry Resource starting in May of 1998. His research focuses on the DNA-drug interaction using mass spectrometric techniques and modified biomolecules. In particular, two types of drugs are under investigation: 1) those which bind via DNA grooves, and 2) those which bind via DNA intercalation. Mass spectrometry will be used to elucidate receptor-ligand binding affinities, ligand binding sites, and ligand binding selectivities.