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SKELETAL REGULATION IN CHILDREN WITH CHRONIC RENAL FAILURE

SKELETAL REGULATION IN CHILDREN WITH CHRONIC RENAL FAILURE
慢性肾功能衰竭儿童的骨骼调节
批准号：
6118464
负责人：
ISIDRO B. SALUSKY
金额：
$0.19万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6118464
关键词：
1,25 dihydroxycholecalciferol bone disorder child (0-11) chronic renal failure clinical research clinical trials hormone regulation /control mechanism human subject human therapy evaluation kidney function parathyroid gland parathyroid hormones pathologic process vitamin therapy

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中文摘要
翻译
骨病是慢性肾衰竭患者常见的并发症。生长迟缓是大多数患者的一个突出的临床特征，骨病是骨骼发育延迟的重要原因。儿童期早期发生肾衰竭的患者通常身高低于年龄调整正常值两个标准差，主要下降发生在生命的头两年。
英文摘要
Bone disease is a frequent complication in patients with chronic renal failure. Growth retardation is a prominent clinical feature in most patients, and bone disease contributes substantially to the delay in skeletal development. Patients who develop renal failure early in childhood commonly have body height two standard deviations below the age-adjusted normal values and the major decline occurs within the first two years of life.
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