4 MONTH BIOMED GRANT LETTER WAS SENT TO D DEERFIELD

4 个月的 Biomed 授权信已发送给 D DEERFIELD

• 批准号: 6221023
• 负责人: Ronald Levy
• 金额: $ 0.13万
• 依托单位: MELLON PITTS CORPORATION (MPC CORP)
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6221023
• 关键词: biological products; biomedical resource; computers; genetics; genome; proteins; virus

Varicella zoster virus encodes several proteins that regulate the growth cycle and the goal of the research is to investigate the domains that influence their functional integrity. The genome of it and several other herpesviruses with better understanding regulatory proteins have been sequenced, allowing comparisons to be made. The software and databases available at the Pittsburgh Supercomputing Center will enable sequence comparisons to be made to identify functional, conserved and diverse regions, and these will be used to correlate function to the structure of these proteins and their interaction with nucleic acids.

水痘带状疱疹病毒编码几种蛋白质，调节 生长周期，研究的目标是调查 影响其功能完整性的域。它的基因组 和其他几种疱疹病毒，对调节 蛋白质已经被测序，可以进行比较。这个 匹兹堡超级计算中心提供的软件和数据库 中心将允许进行序列比较以识别 功能性、保守性和多样性的区域，这些区域将被用于 与这些蛋白质的结构和它们的功能相关 与核酸的相互作用。