课题基金 / 基金详情

RNA-PROTEIN INTERACTIONS

RNA-PROTEIN INTERACTIONS
RNA-蛋白质相互作用
批准号:
6170339
负责人:
Donald H Burke
金额:
$21.64万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-07-15 至 2003-06-30

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中文摘要
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英文摘要
DESCRIPTION (Adapted from applicant's abstract): This is a proposal to create new aptamers to reverse transcriptase via SELEX and to characterize the interaction of these aptamers in detail. Novel approaches to generate chimeric aptamers will be used in the proposed studies and the interaction of these aptamers with RT will be evaluated through the use of several complementary biochemical and physical assays. In addition, experiments will be carried out to see what kinds of RT resistant mutants arise in response to various candidate aptamers.
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会议论文
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
  • 批准号:
    10221727
  • 项目类别:
  • 资助金额:
    $28.86万
  • 财政年份:
    2018
  • 负责人:
    Donald H Burke
  • 依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
  • 批准号:
    9788497
  • 项目类别:
  • 资助金额:
    $28.88万
  • 财政年份:
    2018
  • 负责人:
    Donald H Burke
  • 依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
  • 批准号:
    10387714
  • 项目类别:
  • 资助金额:
    $9.21万
  • 财政年份:
    2018
  • 负责人:
    Donald H Burke
  • 依托单位:
Strain-specific and pan-filoviral aptamer recognition of Ebola virus glycoproteins
  • 批准号:
    9293978
  • 项目类别:
  • 资助金额:
    $23.98万
  • 财政年份:
    2016
  • 负责人:
    Donald H Burke
  • 依托单位:
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