RNA-PROTEIN INTERACTIONS
RNA-PROTEIN INTERACTIONS
批准号:
6170339
负责人:
Donald H Burke
金额:
$21.64万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-07-15 至 2003-06-30
中文摘要
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION (Adapted from applicant's abstract): This is a proposal to create
new aptamers to reverse transcriptase via SELEX and to characterize the
interaction of these aptamers in detail. Novel approaches to generate chimeric
aptamers will be used in the proposed studies and the interaction of these
aptamers with RT will be evaluated through the use of several complementary
biochemical and physical assays. In addition, experiments will be carried out
to see what kinds of RT resistant mutants arise in response to various
candidate aptamers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:10221727
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项目类别:
-
资助金额:$28.86万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:9788497
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项目类别:
-
资助金额:$28.88万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:10387714
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项目类别:
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资助金额:$9.21万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Strain-specific and pan-filoviral aptamer recognition of Ebola virus glycoproteins
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批准号:9293978
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项目类别:
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资助金额:$23.98万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
RNA Aptamers that Differentiate Among HIV-1 Capsid Assembly States
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批准号:9303240
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项目类别:
-
资助金额:$23.03万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
Strain-specific and pan-filoviral aptamer recognition of Ebola virus glycoproteins
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批准号:9181298
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项目类别:
-
资助金额:$18.76万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
EVALUATION OF CANDIDATE VACCINE TECHNOLOGIES USING AGENT BASED COMPUTATIONAL ME
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批准号:8171787
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项目类别:
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资助金额:$0.11万
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财政年份:2010
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7924282
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项目类别:
-
资助金额:$6.08万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
EVALUATION OF CANDIDATE VACCINE TECHNOLOGIES USING AGENT BASED COMPUTATIONAL ME
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批准号:7956315
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项目类别:
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资助金额:$0.08万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7879022
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项目类别:
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资助金额:$5.71万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7801719
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项目类别:
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资助金额:$3.93万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7418746
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项目类别:
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资助金额:$37.06万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:8213487
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项目类别:
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资助金额:$43.12万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Gene Therapy for HIV Using Aptamers that Target Reverse Transcriptase
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批准号:9293218
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项目类别:
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资助金额:$57.91万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7556790
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项目类别:
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资助金额:$41.38万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Gene Therapy for HIV Using Aptamers that Target Reverse Transcriptase
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批准号:8789204
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项目类别:
-
资助金额:$56.91万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7761216
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项目类别:
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资助金额:$43.46万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:8035890
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项目类别:
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资助金额:$43.3万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
RNA aptamers to inhibit natural and evolved RT variants
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批准号:7024610
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项目类别:
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资助金额:$21.53万
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财政年份:2005
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负责人:Donald H Burke
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依托单位:
RNA aptamers to inhibit natural and evolved RT variants
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批准号:6893031
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项目类别:
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资助金额:$18.62万
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财政年份:2005
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负责人:Donald H Burke
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依托单位:
海外基金