EVALUATION OF CANDIDATE VACCINE TECHNOLOGIES USING AGENT BASED COMPUTATIONAL ME
EVALUATION OF CANDIDATE VACCINE TECHNOLOGIES USING AGENT BASED COMPUTATIONAL ME
批准号:
7956315
负责人:
Donald H Burke
金额:
$0.08万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-08-01 至 2010-07-31
关键词:
Biomedical ResearchClinical DataComputer Retrieval of Information on Scientific Projects DatabaseComputer SimulationComputersData CollectionDiseaseEvaluationFoundationsFundingGrantHigh Performance ComputingInstitutionModelingPopulationPublic Health SchoolsResearchResearch PersonnelResourcesSourceSupercomputingTechnologyTimeUnited States National Institutes of HealthUniversitiesVaccinesWorkbasecollegeshared memorysimulationvaccine candidate
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This proposal seeks computational support for our recently funded Bill and Melinda Gates Foundation grant entitled Evaluation of Candidate Vaccine Technologies Using Computational Models. We have assembled a team of researchers from the Graduate School of Public Health at the University of Pittsburgh, Penn State, Imperial College, and the Pittsburgh Supercomputing Center for a unique project that will involve both clinical data collection and computational modeling to help understand how to create vaccine technologies that increase acceptance in key susceptible populations. We are here requesting computational support for the first of the four years of our project to begin the work of creating models to understand the spread of a number of candidate diseases. The support requested is for computer time on the one of the TeraGrids newest machines, Pople, the SGI Altix 4700 at the PSC. The simulations we need to perform require a large amount of shared-memory, which is a unique capability provided by this resource. Justification and estimations of the necessary computations for the upcoming year will be given, and we will also provide justification for Advanced TeraGrid support to assist us in vital aspects of our research, especially in understanding how to most effectively and efficiently use the requested resource.
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会议论文
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:10221727
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项目类别:
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资助金额:$28.86万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:9788497
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项目类别:
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资助金额:$28.88万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Mechanism of Microbial DNA Hypervariation through Mutagenic Transposition
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批准号:10387714
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项目类别:
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资助金额:$9.21万
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财政年份:2018
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负责人:Donald H Burke
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依托单位:
Strain-specific and pan-filoviral aptamer recognition of Ebola virus glycoproteins
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批准号:9293978
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项目类别:
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资助金额:$23.98万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
RNA Aptamers that Differentiate Among HIV-1 Capsid Assembly States
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批准号:9303240
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项目类别:
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资助金额:$23.03万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
Strain-specific and pan-filoviral aptamer recognition of Ebola virus glycoproteins
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批准号:9181298
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项目类别:
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资助金额:$18.76万
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财政年份:2016
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负责人:Donald H Burke
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依托单位:
EVALUATION OF CANDIDATE VACCINE TECHNOLOGIES USING AGENT BASED COMPUTATIONAL ME
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批准号:8171787
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项目类别:
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资助金额:$0.11万
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财政年份:2010
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7924282
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项目类别:
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资助金额:$6.08万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7879022
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项目类别:
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资助金额:$5.71万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7801719
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项目类别:
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资助金额:$3.93万
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财政年份:2009
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7418746
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项目类别:
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资助金额:$37.06万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:8213487
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项目类别:
-
资助金额:$43.12万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Gene Therapy for HIV Using Aptamers that Target Reverse Transcriptase
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批准号:9293218
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项目类别:
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资助金额:$57.91万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7556790
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项目类别:
-
资助金额:$41.38万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Gene Therapy for HIV Using Aptamers that Target Reverse Transcriptase
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批准号:8789204
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项目类别:
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资助金额:$56.91万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:7761216
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项目类别:
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资助金额:$43.46万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
Determinates of anti-HIV nucleic acid aptamer potency and resistance
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批准号:8035890
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项目类别:
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资助金额:$43.3万
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财政年份:2008
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负责人:Donald H Burke
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依托单位:
RNA aptamers to inhibit natural and evolved RT variants
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批准号:7024610
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项目类别:
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资助金额:$21.53万
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财政年份:2005
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负责人:Donald H Burke
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依托单位:
RNA aptamers to inhibit natural and evolved RT variants
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批准号:6893031
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项目类别:
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资助金额:$18.62万
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财政年份:2005
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负责人:Donald H Burke
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依托单位:
RNA-PROTEIN INTERACTIONS
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批准号:6170339
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项目类别:
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资助金额:$21.64万
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财政年份:1999
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负责人:Donald H Burke
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依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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批准号:31070748
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2010
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负责人:Christine Nardini
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依托单位: