NIH-AIDS RESEARCH AND REFERENCE REAGENT PROGRAM

艾滋病试剂项目的目标是获取和分发 艾滋病毒/艾滋病研究的关键试剂，包括机会主义 感染研究和结核病。试剂计划生产这些试剂， 标准化面板和协议；并免费将其提供给 世界各地的调查人员。此外，试剂程序收集 关于艾滋病相关试剂和标准的信息，并传播 通过印刷品、电子媒体和湿工作坊提供这些信息； 通过开发和发布以下内容加强技术转让 方法；并通过以下方式促进试剂的商业化开发 与生物技术和制药公司积极沟通； 并作为联合国艾滋病规划署和联合国艾滋病合作中心参加 王国的MRC艾滋病试剂项目。试剂计划还提供 在处理和运输传染病材料方面提供技术援助。 可用的试剂包括：基因分型的临床和实验室分离株 病毒、细胞系、遗传克隆、DNA文库、表达 载体，单抗和多克隆抗体，重组蛋白， 合成肽，包括聚合酶链式反应标准的参考板，正文 液体和药物标准。自1988年成立以来， 试剂计划已从一小批研究材料演变为 独一无二的资源。贡献者和用户包括来自 美国国立卫生研究院、学术和非营利机构以及工业界。自.以来 1988年，已分发了50,000多种试剂和1,300多种 科学出版物参考使用从以下来源获得的材料 该计划。该方案的成功进一步体现在 扩大用户网络。来自39个国家和地区的1400多名科学家 北美、南美、欧洲、亚洲、非洲和澳大利亚 从该项目注册并获得试剂。

The objective of AIDS Reagent Program is to acquire and distribute critical reagents for HIV/AIDS research including opportunistic infection studies and TB. The Reagent Program produces these reagents, standardized panels, and protocols; and provides them free of charge to investigators worldwide. Additionally, the reagent program collects information about AIDS-related reagents and standards and disseminates this information through print, electronic media, and wet workshops; enhances technology transfer through development and publication of methods; and facilitates commercial development of reagents through proactive communication with biotechnology and pharmaceutical companies; and participates as an AIDS Collaborating Center of UNAIDS and United Kingdom's MRC AIDS Reagent Project. The Reagent Program also provides technical assistance in handling and shipping of infectious materials. Available reagents include: genotyped clinical and laboratory isolates of viruses, cell lines, genetic clones, DNA libraries, expression vectors, monoclonal and polyclonal antibodies, recombinant proteins, synthetic peptides, reference panels including PCR standards, body fluids, and drug standards. Since its establishment in 1988, the Reagent Program has evolved from a small bank of research materials to a unique resource. Contributors and users include scientists from the NIH, academic and non-profit institutions, and from industry. Since 1988, over 50,000 reagents have been distributed and more than 1,300 scientific publications have a referenced use of materials obtained from the Program. The success of the Program is further evident in the expanding network of users. Over 1400 scientists from 39 countries in North and South America, Europe, Asia, Africa, and Australia have registered and obtained reagents from the Program.