NIH-AIDS RESEARCH AND REFERENCE REAGENT PROGRAM

美国国立卫生研究院艾滋病研究和参考试剂计划

• 批准号: 6359361
• 负责人: MARTHA F. MATOCHA
• 金额: $ 95.46万
• 依托单位: FISHER BIOSERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-01-20 至 2005-01-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6359361
• 关键词: AIDS; biomedical resource; reagent /indicator

The objective of AIDS Reagent Program is to acquire and distribute critical reagents for HIV/AIDS research including opportunistic infection studies and TB. The Reagent Program produces these reagents, standardized panels, and protocols; and provides them free of charge to investigators worldwide. Additionally, the reagent program collects information about AIDS-related reagents and standards and disseminates this information through print, electronic media, and wet workshops; enhances technology transfer through development and publication of methods; and facilitates commercial development of reagents through proactive communication with biotechnology and pharmaceutical companies; and participates as an AIDS Collaborating Center of UNAIDS and United Kingdom's MRC AIDS Reagent Project. The Reagent Program also provides technical assistance in handling and shipping of infectious materials. Available reagents include: genotyped clinical and laboratory isolates of viruses, cell lines, genetic clones, DNA libraries, expression vectors, monoclonal and polyclonal antibodies, recombinant proteins, synthetic peptides, reference panels including PCR standards, body fluids, and drug standards. Since its establishment in 1988, the Reagent Program has evolved from a small bank of research materials to a unique resource. Contributors and users include scientists from the NIH, academic and non-profit institutions, and from industry. Since 1988, over 50,000 reagents have been distributed and more than 1,300 scientific publications have a referenced use of materials obtained from the Program. The success of the Program is further evident in the expanding network of users. Over 1400 scientists from 39 countries in North and South America, Europe, Asia, Africa, and Australia have registered and obtained reagents from the Program.

艾滋病试剂计划的目标是获得和分发 艾滋病毒/艾滋病研究的关键试剂，包括机会性 感染研究和结核病。 试剂程序生产这些试剂， 标准化的面板和协议;并免费提供给 全世界的调查员。此外，试剂程序收集 有关艾滋病相关试剂和标准品的信息， 通过印刷品、电子媒体和湿讲习班提供这些信息; 通过编制和出版《技术转让和转让手册》 方法;并通过以下方式促进试剂的商业开发 与生物技术和制药公司积极沟通; 并作为联合国艾滋病规划署和联合国艾滋病规划署的艾滋病合作中心参加 Kingdom的MRC艾滋病试剂项目。 试剂计划还提供 在处理和运输传染性材料方面提供技术援助。 可用试剂包括：基因分型临床和实验室分离株 病毒、细胞系、基因克隆、DNA文库、表达 载体，单克隆和多克隆抗体，重组蛋白， 合成肽，参考板，包括PCR标准品，主体 液体和药物标准品。 自1988年成立以来， 试剂计划已经从一个研究材料的小银行发展到 独一无二的资源贡献者和使用者包括来自 美国国立卫生研究院，学术和非营利机构，以及工业界。 以来 1988年，分发了5万多份试剂， 科学出版物引用了从以下来源获得的材料： 节目 该方案的成功进一步体现在 扩大用户网络。 来自39个国家的1400多名科学家 南北美洲、欧洲、亚洲、非洲和澳大利亚都有 注册并从该计划获得试剂。