ASSESSMENT OF PERIPHERAL BLOOD EOSINOPHILS

外周血嗜酸性粒细胞的评估

• 批准号: 6161566
• 负责人: T A FLEISHER
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6161566
• 关键词: blood disorder diagnosis; blood tests; clinical research; eosinophil; eosinophilia; human subject; immunologic assay /test; monoclonal antibody

An extensive panel of monoclonal antibodies is being used to evaluate and characterize eosinophils in normal subjects and patients with eosinophilia resulting from infection or other causes. The data are being generated using a novel gating approach that was developed by Dr. Nutman's lab. These data are being reviewed for evidence of changes in peripheral eosinophils as a consequence of eosinophil mobilization and disease.

一个广泛的单克隆抗体小组正在被用来评估和 描述正常受试者和嗜酸性粒细胞增多症患者中的嗜酸性粒细胞 由感染或其他原因引起的。数据正在生成 使用了努特曼博士实验室开发的一种新的门控方法。 正在审查这些数据，以寻找外周血细胞变化的证据。 嗜酸性粒细胞动员和疾病的结果。