阿米什人肥胖的遗传学-猫眼课题宝

阿米什人肥胖的遗传学

批准号：

6162610

负责人：

A F WILSON

金额：

$0.0万

依托单位：

NATIONAL HUMAN GENOME RESEARCH INSTITUTE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/6162610

关键词：

Mennonite autosomal dominant trait child (0-11) clinical research family genetics gene expression genetic markers genotype human subject linkage mapping obesity phenotype

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中文摘要

翻译

一项与肥胖有关的测量方法的资料已在网上获得

英文摘要

Information on a measure related to obesity has been obtained on over 3000 Amish individuals. Segregation analysis has been done on the trait with the best fitting model being an autosomal dominant model adjusted for age and sex effects. The model has been used to identify 20 families that will be most informative for linkage analysis. Additional phenotyping will be funded through the German Government. Genotyping will be done in the Medical Genetics Branch of NHGRI. Markers will be determined in an attempt to identify genetic components for traits related to obesity in the Amish.

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