STATISTICAL ANALYSIS OF MOLECULAR GENETICS OF CARDIOVASCULAR DISEASE

该项目的目的是确定基因参与 使用遗传标记和统计遗传学的心血管疾病 分析。所研究的标记物包括用于以下的候选基因的探针： 血管紧张素转换酶、钠-钾-ATP酶、肾素和心钠素 以及匿名的DNA标记。使用来自 辛辛那提大学，模型独立的同胞对连锁分析， 用于识别血液变异中可能涉及的区域 压力措施。样本包括100多个同胞对，主要是 非裔美国人

The purpose of the project is to identify genes involved in cardiovascular disorders using genetic markers and statistical genetic analyses. The markers studied include probes for candidate genes for angiotension converting enzyme, Na-K-ATPase, renin and atrial natriuretic factor, as well as anonymous DNA markers. Using genotyping data from the University of Cincinnati, model-independent sib pair linkage analysis was used to identify possible regions involved in the variation of blood pressure measures. The sample includes over 100 sib pairs, primarily African-Americans.